Identification of novel mycocompounds as inhibitors of PI3K/AKT/mTOR pathway against RCC

Autor:	Ravi Prakash Yadav, Srilagna Chatterjee, Arindam Chatterjee, Dilip Kumar Pal, Sudakshina Ghosh, Krishnendu Acharya, Madhusudan Das
Rok vydání:	2022
Předmět:	Cell Biology Molecular Biology Biochemistry
Zdroj:	Journal of Receptors and Signal Transduction. 42:599-607
ISSN:	1532-4281 1079-9893
DOI:	10.1080/10799893.2022.2123515
Popis:	PI3K/AKT/mTOR pathway is one of the frequently disrupted signaling pathways in renal cell carcinoma (RCC) that plays a significant role in tumor formation, disease progression and therapeutic resistance. Therefore, novel natural molecules targeting the critical proteins of this pathway will provide the best alternative to existing drugs, which are toxic and develops resistance. Recent studies have recognized the anti-cancer therapeutic potential of mycocompounds. The current study is focused on screening various mycocompounds from
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e35bd42b6ea35a2a3c2e7f227b885d https://doi.org/10.1080/10799893.2022.2123515 Zobrazit plný text záznamu