Advances in the understanding and clinical management of mastocytosis and clonal mast cell activation syndromes
| Autor: | Alberto Orfao, Luis Escribano, Almudena Matito, David González-de-Olano |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Photodermatology & Skin Aging Review Bioinformatics General Biochemistry Genetics and Molecular Biology Allergy & Hypersensitivity Immunomodulation 03 medical and health sciences Immunopharmacology & Hematologic Pharmacology 0302 clinical medicine Leukocyte Signaling & Gene Expression Genetics of the Immune System Medicine General Pharmacology Toxicology and Pharmaceutics Systemic mastocytosis General Immunology and Microbiology business.industry Mast cell activation Cutaneous Signs of Systemic Disease General Medicine Articles Mast Cell Activation Syndromes medicine.disease Management Treatment 030104 developmental biology medicine.anatomical_structure 030228 respiratory system Immunology Clinical Immunology Bone marrow business Mastocytosis |
| Zdroj: | F1000Research Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid Consejería de Sanidad de la Comunidad de Madrid |
| ISSN: | 2046-1402 |
| Popis: | Clonal mast cell activation syndromes and indolent systemic mastocytosis without skin involvement are two emerging entities that sometimes might be clinically difficult to distinguish, and they involve a great challenge for the physician from both a diagnostic and a therapeutic point of view. Furthermore, final diagnosis of both entities requires a bone marrow study; it is recommended that this be done in reference centers. In this article, we address the current consensus and guidelines for the suspicion, diagnosis, classification, treatment, and management of these two entities. |
| Databáze: | OpenAIRE |
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