Valve Repair Improves Central Sleep Apnea in Heart Failure Patients With Valvular Heart Diseases
Autor: | Hideo Tsunemoto, Kyohei Yamazaki, Masafumi Takahashi, Jun Koyama, Uichi Ikeda, Seiichiro Eda, Mamoru Kamikozawa, Hidetoshi Abe, Hironobu Yaegashi, Hiroto Kitahara |
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Rok vydání: | 2009 |
Předmět: |
Male
Cardiac function curve Cardiac Catheterization medicine.medical_specialty Central sleep apnea Polysomnography medicine.medical_treatment Heart Valve Diseases Catheterization Internal medicine medicine Humans Pulmonary Wedge Pressure Aged Cardiac catheterization Heart Failure Sleep Apnea Obstructive medicine.diagnostic_test business.industry Sleep apnea General Medicine Middle Aged medicine.disease Sleep Apnea Central Cardiac surgery Obstructive sleep apnea Echocardiography Aortic Valve Heart Valve Prosthesis Anesthesia Heart failure cardiovascular system Cardiology Mitral Valve Female Cardiology and Cardiovascular Medicine business |
Zdroj: | Circulation Journal. 73:2148-2153 |
ISSN: | 1347-4820 1346-9843 |
Popis: | Background: Recent studies suggest that treatment of heart failure (HF) could improve cardiac function and sleep apnea syndrome (SAS), but it is unknown how cardiac surgery may affect SAS in HF patients. Relationships between HF with valvular heart diseases and 2 types of SAS (obstructive sleep apnea (OSA) and central sleep apnea (CSA)) were examined. The effects of valve repair surgery on OSA and CSA was also investigated. Methods and Results: Polysomnography, echocardiography and right cardiac catheterization were used to study 150 severe HF patients with mitral valvular and/or aortic valvular diseases. Significant associations between SAS and age, gender, body mass index, or hypertension were observed. The value of the CSA-apnea index (AI) was significantly correlated with pulmonary capillary wedge pressure (PCWP) and mean pulmonary artery pressure (PAP). These associations were not identified for OSA-AI. Valve repair surgery was used to treat 74 patients with severe SAS. The treatment led to a significant improvement in PCWP and mean PAP, and CSA-AI, but not in OSA-AI. Conclusions: These findings suggest close associations between CSA and cardiac function in HF patients with valvular heart diseases. Furthermore, improvement of cardiac function with valvular surgery reduces the severity of CSA in HF patients with valvular heart diseases. (Circ J 2009; 73: 2148-2153) |
Databáze: | OpenAIRE |
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