The first report of animal genotypes of Cryptosporidium parvum in immunosuppressed and immunocompetent humans in Slovakia
| Autor: | Michaela Špalková, Alexandra Valenčáková, Lenka Luptakova, Jana Kalinová, Juliana Gabzdilová, Vojtech Boldiš, František Ondriska, Kinga Dedinská, Monika Halánová, Veronika Bednarova, Elena Hatalová |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Diarrhea Slovakia Adolescent Genotype 040301 veterinary sciences medicine.medical_treatment Cryptosporidiosis Group A Group B 0403 veterinary science 03 medical and health sciences Immunocompromised Host Young Adult parasitic diseases medicine Humans In patient Child Feces 030304 developmental biology Cryptosporidium parvum 0303 health sciences General Veterinary General Immunology and Microbiology biology business.industry Immunosuppression Cryptosporidium 04 agricultural and veterinary sciences General Medicine Middle Aged biology.organism_classification Virology Child Preschool business Immunocompetence |
| Zdroj: | Transboundary and emerging diseases. 66(1) |
| ISSN: | 1865-1682 |
| Popis: | The aim of our study was to determine species and genotypes of Cryptosporidium in patients suffering from immunosuppressive illnesses, but also in immunocompetent patients suffering from diarrhoea. A total of 80 samples of faeces were collected from both immunosuppressed and immunocompetent patients. The immunosuppressed patients (65 samples) - 35 adult patients (group A) and 30 children (group B) were hospitalized at the Clinic of Oncohemathology. Samples from immunocompetent humans (15 samples, group C) were taken from patients with clinical signs of acute diarrhoea. With the use of molecular methods targeting the 60 kDa glycoprotein (GP60) gene region, we have identified multiple genotypes of Cryptosporidium. parvum and Cryptosporidium. hominis in immunocompromised, but also in immunocompetent individuals (C. hominis IbA10G2, IeA12G3T3; C. parvum IIaA10G1R1, IIaA11G2R1, IIaA12G2R1, IIaA13G1R1, IIaA14G1R1, IIaA14G2R1, IIaA17G1R1 and IIaA18G1R1). This is the first report of the occurrence of genotypes IIaA10G1R1, IIa12G2R1 and IIaA18G1R1 in human hosts. |
| Databáze: | OpenAIRE |
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