Antioxidant and antimicrobial activities of various extracts from Stachys cretica subsp. bulgarica Rech.f., Stachys byzantina K. Koch and Stachys thirkei K. Koch

Autor: GULSOY TOPLAN, Gizem, TAŞKIN, Turgut, MATARACI KARA, Emel, GENÇ, Gülay Ecevit
Přispěvatelé: GÜLSOY TOPLAN G., TAŞKIN T., MATARACI KARA E., ECEVİT GENÇ G., İstinye Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Gülsoy Toplan, Gizem, Gizem Gülsoy Toplan / ECA-5991-2022, Gizem Gülsoy Toplan / 57192304526
Rok vydání: 2021
Předmět:
Zdroj: Volume: 51, Issue: 3 341-347
İstanbul Journal of Pharmacy
ISSN: 2587-2087
DOI: 10.26650/istanbuljpharm.2021.974035
Popis: Background and Aims: Stachys L. species, which are members of the Lamiaceae family, have long been applied for their therapeutic benefits especially to cure cough, infection, genital tumors, ulcers, inflammatory illnesses, and wounds in Anatolian traditional medicine. In the current study, various extracts prepared from the aerial parts of Stachys cretica subsp. butgarica Rech.f. (SC), Stachys byzantina K. Koch (SB), Stachys thirkei K. Koch and were tested for their in vitro antioxidant, antibacterial, and anticandidat properties. Methods: The aerial parts of three Stachys species were sequentially extracted using n-hexane, chloroform, and methanol. Aqueous extracts of each sample was also prepared by infusion process. The total phenolic content of each extract was determined and the contribution of the biological activities in the samples was evaluated. To assess the antioxidant capacity, samples were studied using CUPRAC activity, DPPH center dot free radical scavenging, and FRAP methods. The antimicrobial activity of the extracts was tested against 7 bacteria and 3 yeast. Results: The infusion and methanol extract exhibited the strongest antioxidant potential and also had the highest percentage of phenolics among the studied extracts. The n-hexane extracts of all studied species showed considerable antifungal activity with MIC values ranging from 312.5-78.12 mg/L. Conclusion: According to our results, three Stachys species were found to be beneficial for their antioxidant and antimicrobial properties. Background and Aims: Stachys L. species, which are members of the Lamiaceae family, have long been applied for their therapeutic benefits especially to cure cough, infection, genital tumors, ulcers, inflammatory illnesses, and wounds in Anatolian traditional medicine. In the current study, various extracts prepared from the aerial parts of Stachys cretica subsp. butgarica Rech.f. (SC), Stachys byzantina K. Koch (SB), Stachys thirkei K. Koch and were tested for their in vitro antioxidant, antibacterial, and anticandidat properties. Methods: The aerial parts of three Stachys species were sequentially extracted using n-hexane, chloroform, and methanol. Aqueous extracts of each sample was also prepared by infusion process. The total phenolic content of each extract was determined and the contribution of the biological activities in the samples was evaluated. To assess the antioxidant capacity, samples were studied using CUPRAC activity, DPPH center dot free radical scavenging, and FRAP methods. The antimicrobial activity of the extracts was tested against 7 bacteria and 3 yeast. Results: The infusion and methanol extract exhibited the strongest antioxidant potential and also had the highest percentage of phenolics among the studied extracts. The n-hexane extracts of all studied species showed considerable antifungal activity with MIC values ranging from 312.5-78.12 mg/L. Conclusion: According to our results, three Stachys species were found to be beneficial for their antioxidant and antimicrobial properties. WOS:000744167900009
Databáze: OpenAIRE
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