Gastroparesis with concomitant gastrointestinal dysmotility is not a contraindication for per-oral pyloromyotomy (POP)
| Autor: | Alisan Fathalizadeh, Kevin El-Hayek, Matthew T. Allemang, Chao Tu, John Rodriquez, Michael Cline, Abhiram Kondajji, Michael Klingler, Rebecca Kelley |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Gastroparesis medicine.medical_treatment Pyloromyotomy Gastroenterology Internal medicine medicine Humans Contraindication Gastrointestinal dysmotility Retrospective Studies Gastric emptying business.industry Contraindications Hepatology Middle Aged medicine.disease Treatment Outcome Gastric Emptying Concomitant Surgery Female business Abdominal surgery |
| Zdroj: | Surgical endoscopy. 36(6) |
| ISSN: | 1432-2218 |
| Popis: | Per-oral pyloromyotomy (POP or G-POEM) provides significant short-term improvements in symptoms and objective emptying for patients with medically refractory gastroparesis, but it is unclear if patients with gastroparesis and co-existing dysmotility (small bowel or colonic delay) also benefit. In this study, we used wireless motility capsule (WMC) data to measure outcomes in patients with isolated gastroparesis (GP) and gastroparesis with co-existing dysmotility (GP + Dys) who underwent POP. We retrospectively analyzed patients who had POP and completed WMC data during their evaluation of intestinal dysmotility. WMC data were reviewed to identify patients who demonstrated isolated GP or GP + Dys. Each patient's pre-op and post-op Gastroparesis Cardinal Symptom Index (GCSI) and 4-h solid-phase scintigraphy gastric emptying studies (GES) scores were compared to evaluate improvement. Of the entire cohort (n = 73), 89% were female with a mean age of 47.0 ± 15.0 years old. Gastroparesis etiologies were divided among idiopathic (54.8%), diabetic (26%), postsurgical (8.2%), autoimmune (5.5%), and multifactorial (5.5%). Forty-one patients (56%) had GP and 32 patients (44%) had GP + Dys. GCSI improved after POP whether the patient had isolated GP (− 12.31, p |
| Databáze: | OpenAIRE |
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