Outcome in critically ill patients with candidal fungaemia: Candida albicans vs. Candida glabrata
| Autor: | Eric Hoste, Francis Colardyn, Jan Poelaert, K Vandewoude, Stijn Blot |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
Microbiology (medical) medicine.medical_specialty Antifungal Agents Adolescent Critical Illness Population Internal medicine Intensive care Candida albicans Severity of illness medicine Humans Hospital Mortality education Fungemia Aged Candida Retrospective Studies Aged 80 and over Cross Infection education.field_of_study biology Candida glabrata business.industry Candidiasis General Medicine Middle Aged biology.organism_classification medicine.disease Corpus albicans Surgery Intensive Care Units Logistic Models Infectious Diseases business Fluconazole medicine.drug |
| Zdroj: | Journal of Hospital Infection. 47:308-313 |
| ISSN: | 0195-6701 |
| DOI: | 10.1053/jhin.2000.0918 |
| Popis: | In a retrospective study (1 January 1992-12 December 1998), we investigated population characteristics and outcome in critically ill patients with fungaemia involving C. albicans (n=41) and C. glabrata (n=15). Patients with C. glabrata fungaemia were significantly older compared with patients in the C. albicans group (P=0.024). There were no other differences in population characteristics or severity of illness. Logistic regression analysis showed age (P=0.021), the presence of a polymicrobial blood stream infection (P=0.039), and renal failure (P=0.044) to be independent predictors of mortality. There was no significant difference in in-hospital mortality between the C. glabrata and C. albicans groups (60.0% vs. 41.5%; P=0.24). Since age was an independent predictor of mortality, the trend towards a higher mortality in patients with C. glabrata can be explained by this population being significantly older. In conclusion, we found no difference in mortality between patients with fungaemia involving C. albicans and C. glabrata. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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