Supplementary Materials and Methods, Figures 1 - 4, Table 1 from Tumor-Infiltrating Myeloid Cells Activate Dll4/Notch/TGF-β Signaling to Drive Malignant Progression

Autor: Giovanna Tosato, Dragan Maric, David Sánchez-Martín, Hyeongil Kwak, Ombretta Salvucci, Dunrui Wang, Kan Jiang, Hidetaka Ohnuki
Rok vydání: 2023
DOI: 10.1158/0008-5472.22401303
Popis: PDF file - 1522KB, Supplementary Figure S1: shows the kinetics of EL4, LLC1 and B16F10 tumor growth in WT and Gfi1-KO mice. Supplemental Figure S2: analysis of EL4 and LLC1 tumor vascularization (A); distribution and typical profiles of CD11b+Ly6C+Ly6G- and CD11b+Ly6C+Ly6G+ in spleen and bone marrow of naive and tumor-bearing mice (B-F). Supplementary Figure S3: typical sorting profiles of LLC1 tumorinfiltrating cell populations (A); expression profiles of Notch ligands and receptors in tumor cells and tumor-infiltrating populations (B); cartoon representation of interacting Notch ligands and receptors. Supplementary Figure S4: kinetic analysis of tumor growth with or without DAPT. Supplementary Table 1: Extensive gene expression profiling by qPCR.
Databáze: OpenAIRE