Immunity status against poliomyelitis in persons 13–14 years old living in Rome
| Autor: | Gaetano Maria Fara, Santi Al, Vescia N, A. Fabrizi, Patti Am, I. Mastroeni, S. Squarcione, A. Marinaro Manduca |
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| Rok vydání: | 1997 |
| Předmět: |
Secondary
Pediatrics medicine.medical_specialty Adolescent Rome Immunization Secondary Booster dose International Units neutralizing antibodies poliomyelitis Antibodies Viral Humans Poliomyelitis Poliovirus Antibodies Herd immunity Serology Immunity medicine Viral General Veterinary General Immunology and Microbiology biology business.industry Public Health Environmental and Occupational Health medicine.disease Infectious Diseases Humoral immunity Immunology biology.protein Molecular Medicine Immunization Viral disease Antibody business |
| Zdroj: | Vaccine. 15:747-750 |
| ISSN: | 0264-410X |
| Popis: | The immunity against poliomyelitis in 1000 subjects 13-14 years old was evaluated. Neutralizing antibodies against poliovirus type 1, 2 and 3 were detected in 97.6%, 95.8% and 70% of samples, respectively. 3/1000 (0.3%) subjects were simultaneously seronegative to the three types. WHO does not suggest a protective level of International Units (IU), but our data indicate that such level is 0.45 IU for polio type 1, 0.65 IU for the type 2 and 0.138 for the type 3. A booster dose of vaccine in adolescence to ensure personal and herd immunity is recommended. |
| Databáze: | OpenAIRE |
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