Patterns of Epidermal Growth Factor Receptors in Basal and Squamous Cell Carcinoma
| Autor: | June K. Robinson, Elizabeth A. Springer |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Keratinocytes
Cytoplasm Pathology medicine.medical_specialty Skin Neoplasms Cell Dermatology Immunoenzyme Techniques Basal (phylogenetics) Epidermal growth factor medicine Humans Basal cell carcinoma Receptor Skin Immunoperoxidase business.industry Cell Membrane medicine.disease Staining ErbB Receptors medicine.anatomical_structure Oncology Carcinoma Basal Cell Carcinoma Squamous Cell Immunohistochemistry business |
| Zdroj: | The Journal of Dermatologic Surgery and Oncology. 17:20-24 |
| ISSN: | 0148-0812 |
| DOI: | 10.1111/j.1524-4725.1991.tb01588.x |
| Popis: | The presence of immunoreactive epidermal growth factor receptors in human skin tumors was investigated using the indirect immunoperoxidase technique. Sixteen basal cell carcinomas and 11 squamous cell carcinomas were evaluated. All of the specimens studied were receptor positive. In 70% of the specimens there was prominent staining of the cell membranes. In 54% of the nodular basal cell carcinoma specimens there was increased staining at the periphery of the tumor cell masses. |
| Databáze: | OpenAIRE |
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