Mid-term evaluation of perioperative i.v. corticosteroid treatment efficacy on overall and audiological outcome following CO2 laser stapedotomy: a retrospective study of 84 cases
| Autor: | Zoltán Fent, T Szalóki, L Székely, Gábor Polony, Kornél Dános, Anita Gáborján, László Tamás |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty CO2 laser Corticosteroid treatment Middle ear Otology Methylprednisolone Perioperative Care medicine Humans Hearing Loss Infusions Intravenous Glucocorticoids Stapedotomy Retrospective Studies Stapes surgery business.industry Retrospective cohort study General Medicine Perioperative Audiology Middle Aged medicine.disease Corticosteroid therapy Surgery medicine.anatomical_structure Otosclerosis Treatment Outcome Otorhinolaryngology Lasers Gas Audiometry Pure-Tone Female Neurosurgery Laser Therapy business medicine.drug |
| Zdroj: | European Archives of Oto-Rhino-Laryngology |
| ISSN: | 1434-4726 0937-4477 |
| Popis: | Purpose Our aim was to determine whether perioperatively administered corticosteroid treatment has any beneficial effect on the outcome of stapes surgery, with special regard to the audiological results and early postoperative morbidity. Methods 84 CO2 laser stapedotomies performed in our institute between 2013 and 2018 were included in our investigation. All cases underwent preoperative and mid-term postoperative pure-tone audiometric evaluation. Vestibular complications were also evaluated. The cases were subdivided into two groups, 23 patients received perioperative i.v. methylprednisolone treatment (“S”) while the other 61 patients (“nS”) did not receive any adjuvant pharmacological therapy. The data were analyzed retrospectively using IBM SPSS Statistics. Results CO2 laser stapedotomy proved to be a successful intervention with a significant improvement in ABG and AC thresholds as well. Long-term BC levels were significantly better compared to preoperative ones in the S group; however, in the nS group, no difference could be shown. Hearing and ABG gain were significantly superior in group S [28.1 dB (SD11.2) vs. 18.1 dB (SD 10.9) and 23.9 dB(SD 9.8) vs. 17.2 dB (SD 9.5), respectively]. Conclusion No significant inner ear damage was detectable in the results of our CO2 laser stapedotomy method; however, the positive effect of corticosteroid treatment could be demonstrated through the postoperative hearing levels. We found no statistical difference in early postoperative morbidity. According to our data, the routine administration of corticosteroids during stapes surgery could be an issue worthy of consideration. The effects of perioperative treatment vs that on the first day after surgery, and topical vs. systemic treatment could be the subject of further investigation in a prospective manner. |
| Databáze: | OpenAIRE |
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