A Case of HTLV-I-associated Myelopathy with IgA Nephropathy and Pseudohypoparathyroidism Type 1
| Autor: | Yumiko Arimura, Shigetsugu Noguchi, Yuichiro Yasumoto, Satoshi Takenaga, Kiyoshige Niina, Ken Sonoda, Mitsuhiro Osame, Yoshihiro Yoshida |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Adult
medicine.medical_specialty Skin erythema urologic and male genital diseases Gastroenterology Short stature Nephropathy Excretion immune system diseases Intellectual Disability Internal medicine medicine Humans Growth Disorders Pseudohypoparathyroidism business.industry Glomerular mesangium Glomerulonephritis IGA Glomerulonephritis Genitalia Female General Medicine medicine.disease Paraparesis Tropical Spastic Endocrinology Htlv i associated myelopathy Female medicine.symptom business |
| Zdroj: | Japanese Journal of Medicine. 30:582-587 |
| ISSN: | 1881-123X 0021-5120 |
| DOI: | 10.2169/internalmedicine1962.30.582 |
| Popis: | We report a case of HAM/TSP presenting with short stature, mental retardation, skin eruptions, uterine and ovarian hypogenesis and nephropathy. Skin erythema was noted since from the age of three years old and spasticity of lower extremities from elementary school age. Serum calcium level showed 4.1 mEq/l. Recombinant human PTH infusion resulted in no response of phosphate excretion. The persistent proteinuria prompted renal needle biopsy, which revealed IgA and C1q deposits in glomerular mesangium. A diagnosis of pseudohypoparathyroidism and IgA nephropathy was entertained. This patient with pseudohypoparathyroidism who has a deficient immune system was seized with the early onset of HAM/TSP and IgA nephropathy. |
| Databáze: | OpenAIRE |
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