Clinical Evaluation of Analgesic Activity of Guduchi (Tinospora Cordifolia) Using Animal Model
| Autor: | Nishant Pathak, Rakesh Chandra Chaurasia, Bhomik Goel, Sanjay Kumar Singh, Dwividendra Kumar Nim, Rakesh Kumar Dixit |
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| Rok vydání: | 2014 |
| Předmět: |
anti-nociceptive
Clinical Biochemistry Analgesic lcsh:Medicine Tinospora cordifolia Pharmacology guduchi tinospora cordifolia Animal model Medicine pain Hot plate Anti nociceptive Pharmacology Section biology Traditional medicine business.industry lcsh:R writhing General Medicine analgesic biology.organism_classification hot plate method Pentazocine Ill health business Clinical evaluation medicine.drug |
| Zdroj: | Journal of Clinical and Diagnostic Research, Vol 8, Iss 8, Pp HC01-HC04 (2014) |
| ISSN: | 2249-782X |
| DOI: | 10.7860/jcdr/2014/9207.4671 |
| Popis: | Introduction: Pain is a very well-known signal of ill health and analgesics are the drugs that are used to relieve pain. The main problem with these drugs remains that of side effects. Safer alternatives are natural herbs. Guduchi (Tinospora cordifolia) is one such plant with analgesic potential but few studies are there. Objective: To evaluate the analgesic activity of commercially available extract of Guduchi (T. cordifolia). Materials and Methods: For this purpose commercially available extract of Guduchi (T. cordifolia) by Himalaya Drug Company, Bangalore was used. Albino rats were divided randomly in three groups of six rats each. Group 1 (control) received distilled water orally, group 2 (test) received T. cordifolia extract in dose of 300 mg/kg orally and group 3(standard) received Pentazocine in dose 10mg/kg intraperitoneally. Analgesic activity was evaluated using hot plate and abdominal writhing method. All the observations were analysed statistically using student’s t-test. Observation and Results: T. cordifolia extract significantly (p |
| Databáze: | OpenAIRE |
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