Detrimental effect of oral contraceptives on parameters of bone mass and geometry in a cohort of 248 young women
| Autor: | Manfred Hartard, Michael Wiseman, Christine Kleinmond, Reinhold G. Erben, Ernst Rainer Weissenbacher, Dieter Felsenberg |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
musculoskeletal diseases Peak bone mass Histology Adolescent Physiology Endocrinology Diabetes and Metabolism Population Dentistry Absorptiometry Photon Bone Density Humans Medicine Tibia Quantitative computed tomography education Femoral neck Bone mineral education.field_of_study Lumbar Vertebrae medicine.diagnostic_test Femur Neck business.industry Anthropometry musculoskeletal system Cross-Sectional Studies medicine.anatomical_structure Cohort Female business Contraceptives Oral |
| Zdroj: | Bone. 40:444-450 |
| ISSN: | 8756-3282 |
| Popis: | The aim of this cross-sectional analysis was to examine the skeletal effects of low-dose monophasic oral contraceptive (OC) use in a cohort of 248 young Caucasian women aged 18-24 years. Areal bone mineral density (BMD) of the femoral neck and lumbar spine was evaluated by dual-energy X-ray absorptiometry. Volumetric BMD, bone mineral content (BMC), and bone geometry were assessed in the tibia by peripheral quantitative computed tomography (pQCT). The women were allocated into ever or never OC users, and also into 5 different OC groups according to duration and time of initiation of OC use. Women with >2 years of OC use and OC initiation within 3 years after menarche were characterized by 10% lower femoral neck areal BMD (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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