Prognostic value of cardiopulmonary exercise testing in patients with transthyretin cardiac amyloidosis

Autor: Maria Vittoria Silverii, Alessia Argirò, Samuele Baldasseroni, Carlo Fumagalli, Mattia Zampieri, Ludovica Guerrieri, Simone Bartolini, Carlotta Mazzoni, Costanza Burgisser, Alessia Tomberli, Carlo Di Mario, Niccolò Marchionni, Iacopo Olivotto, Federico Perfetto, Francesco Fattirolli, Francesco Cappelli
Rok vydání: 2022
Předmět:
Zdroj: Internal and emergency medicine.
ISSN: 1970-9366
Popis: The aim of this study is to evaluate the prognostic value of cardiopulmonary testing (CPET) in a cohort of patients with transthyretin cardiac amyloidosis (ATTR-CA). ATTR-CA is associated with a progressive reduction in functional capacity. The prognostic role of CPET parameters and in particular of normalized peak VO2 (%ppVO2) remains to be thoroughly evaluated. In this study, 75 patients with ATTR-CA underwent cardiological evaluation and CPET in a National Referral Center for cardiac amyloidosis (Careggi University Hospital, Florence). Fifty-seven patients (76%) had wild-type ATTR. Median age was 80 (75-83) years, 68 patients (91%) were men. Peak oxygen consumption (14.1 ± 4.1 ml/kg/min) and %ppVO
Databáze: OpenAIRE