Synthesis and antioxidant activity of quinolinobenzothiazinones
| Autor: | R. M. Samarth, M. Kumar, Abhijeet Kumar, K. D. Sharma |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Annulation
Antioxidant Free Radicals DPPH Stereochemistry medicine.medical_treatment Thiazines Chemical synthesis Antioxidants Mice chemistry.chemical_compound Picrates Drug Discovery medicine Animals Organic chemistry Benzothiazoles Pharmacology ABTS Biphenyl Compounds Organic Chemistry Free Radical Scavengers General Medicine Glutathione chemistry Quinolines Lactam Lipid Peroxidation Sulfonic Acids Pharmacophore human activities |
| Zdroj: | European Journal of Medicinal Chemistry. 45:4467-4472 |
| ISSN: | 0223-5234 |
| DOI: | 10.1016/j.ejmech.2010.07.006 |
| Popis: | A new series of structurally diverse quinolinobenzothiazinones has been synthesized with the annulation of heterocyclic structural pharmacophores. The synthesized quinolinobenzothiazinones have been evaluated for their antioxidant (LPO & GSH) and radical scavenging activities (DPPH and ABTS assays). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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