Environmental Exposure of Arsenic in Groundwater Associated to Carcinogenic Risk in Underweight Children Exposed to Fluorides
| Autor: | Enrique Castañeda, Martina Nevárez-Rascón, Lizet Jarquin-Yañez, Nelly Molina-Frechero, Marcela Vergara-Onofre, Ronell Bologna-Molina, Omar Tremillo-Maldonado, Enrique Gaona, Rey Gutiérrez-Tolentino |
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| Přispěvatelé: | Molina-Frechero Nelly, Nevarez-Rascón Martina, Tremillo-Maldonado Omar, Vergara-Onofre Marcela, Gutiérrez-Tolentino Rey, Gaona Enrique, Castañeda Enrique, Jarquin-Yañez Lizet, Bologna-Molina Ronell, Universidad de la República (Uruguay). Facultad de Odontología |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Health
Toxicology and Mutagenesis lcsh:Medicine 010501 environmental sciences 01 natural sciences Hazard quotient Fluorides 0302 clinical medicine Neoplasms Medicine Ingestion 030212 general & internal medicine Child Groundwater education.field_of_study Environmental exposure Carcinogenic risk Underweight medicine.symptom Environmental Monitoring Adult Population chemistry.chemical_element Risk Assessment Article Arsenic 03 medical and health sciences Thinness Environmental health non-carcinogenic Humans Cities education Mexico Carcinogen hazard quotient 0105 earth and related environmental sciences business.industry Drinking Water lcsh:R Public Health Environmental and Occupational Health arsenic carcinogenic risk Environmental Exposure Non-carcinogenic Arsenic contamination of groundwater chemistry exposure dose Exposure dose business Water Pollutants Chemical |
| Zdroj: | International Journal of Environmental Research and Public Health, Vol 17, Iss 3, p 724 (2020) International Journal of Environmental Research and Public Health Volume 17 Issue 3 COLIBRI Universidad de la República instacron:Universidad de la República |
| ISSN: | 1660-4601 |
| Popis: | Background: The purpose of this study was to determine the concentration of inorganic arsenic (As) in the potable water available to the population to be able to estimate the non-carcinogenic risks for underweight children and the carcinogenic risk for adults exposed to As intake who live in the Mezquital municipality, Durango, Mexico. Methods: The As content was quantifed in the water supply sources for human use and its intake was estimated in Mezquital population, southern Durango. With the data obtained, the hazard quotient (HQ) was calculated to determine the non-carcinogenic risk to develop chronic systemic effects in underweight children. The Environmental Protection Agency (EPA) reference health values estimating As exposure risk are from 0.0003 mg/kg/day (non-carcinogenic) to 1.5 mg/kg/day (carcinogenic risk). Results: The analyzed waters presented as concentrations that varied from 0.3 to 10.2 µ g/L, with a mean of 7.35 µ g/L (CI 95% 6.27&ndash 8.38). The exposure dose was 0.4 to 1.36, and the HQ was 1.90 to 6.48 mg/kg/day, the estimated carcinogenic risk from adults varied from 1.28 to 4.37E&minus 4, with values of 3.74&ndash 4.37E&minus 4 mg/kg/day in central area. Conclusions: The children are at risk to develop chronic systemic effects due to ingestion of As from water. |
| Databáze: | OpenAIRE |
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