Unrecognized Drug-Drug Interactions: A Cause of Intraoperative Cardiac Arrest?
| Autor: | Eric M. Thorn, Denis L. Bourke, Neil B. Sandson, Catherine Marcucci |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Male
Drug medicine.medical_specialty business.industry Local anesthetic medicine.drug_class media_common.quotation_subject Intraoperative cardiac arrest Middle Aged Drug interaction Heart Arrest Anesthesiology and Pain Medicine Axillary block Anesthesia Humans Medicine Drug Interactions Intraoperative Complications business Intensive care medicine media_common |
| Zdroj: | Anesthesia & Analgesia. 102:1569-1572 |
| ISSN: | 0003-2999 |
| DOI: | 10.1213/01.ane.0000204290.54768.cc |
| Popis: | Many physicians overlook, or are unaware of, most drug-drug interactions. In our patient, the local anesthetic used for an axillary block may have been the precipitating drug in a cascade of drug-drug interactions that resulted in a cardiac arrest. The combination of multiple preoperative drug-drug interactions prevented the return of a stable native cardiac rhythm for almost 24 h. The mechanisms of interactions of these frequently used drugs are described, and the reader is guided to sources that identify and simplify the understanding of potentially dangerous drug-drug interactions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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