Langerhans Cell Histiocytosis with Extensive Spinal and Thyroid Gland Involvement Presenting with Quadriparesis: An Unusual Case in an Adult Patient
| Autor: | Ahmad Sabri O, Mohd Ariff S, Joehaimey J, Zulmi W |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Cord Langerhans Cell Histiocytosis Langerhans cell histiocytosis Spine Tumours medicine Orthopedics and Sports Medicine Thyroid mass Orthopedic surgery Unusual case business.industry Thyroid Cord Compression With Quadriparesis medicine.disease Mr imaging Thyroid Mass medicine.anatomical_structure Emergency Medicine Immunohistochemistry Surgery Differential diagnosis business RD701-811 Research Article |
| Zdroj: | Malaysian Orthopaedic Journal, Vol 5, Iss 3, Pp 28-31 (2011) |
| ISSN: | 1985-2533 |
| DOI: | 10.5704/moj.1111.004 |
| Popis: | Langerhans cell histiocytosis of the spine frequently presents as a solitary lesion and rarely results in neurological deficit. Involvement of thyroid tissue is also rare, even in multifocal disease presentations. We present an unusual variant of Langerhans cell histiocytosis in a 37-year-old man presenting with profound quadriparesis and incidental thyroid involvement. MR imaging and skeletal radiographs revealed widespread involvement of the spine. The patient underwent surgical resection of the tumour and stabilization of the spine. Diagnosis was confirmed by histological and immunohistochemistry analysis. Langerhans cell histiocytosis should be included in the differential diagnosis of radiolucent lesions of the spine in adults. KEY WORDS Langerhans Cell Histiocytosis, Spine Tumours, Thyroid Mass, Cord Compression With Quadriparesis, Adult. |
| Databáze: | OpenAIRE |
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