Efficacy of Ascorbic Acid (Vitamin C) and/N-Acetylcysteine (NAC) Supplementation on Nutritional and Antioxidant Status of Male Chronic Obstructive Pulmonary Disease (COPD) Patients
| Autor: | Suzana Shahar, Nor Fadilah Rajab, Roslina Abdul Manap, Elham Pirabbasi, Zahara Abdul Manaf |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty Pathology Antioxidant medicine.medical_treatment Medicine (miscellaneous) Nutritional Status Ascorbic Acid Gastroenterology Antioxidants law.invention Body Mass Index Acetylcysteine 03 medical and health sciences Pulmonary Disease Chronic Obstructive Randomized controlled trial law Internal medicine Dietary Carbohydrates Medicine Humans Single-Blind Method Vitamin A Aged COPD Nutrition and Dietetics Vitamin C business.industry Malaysia Middle Aged Ascorbic acid medicine.disease Glutathione Clinical trial 030104 developmental biology Treatment Outcome Dietary Supplements business Body mass index medicine.drug |
| Zdroj: | Journal of nutritional science and vitaminology. 62(1) |
| ISSN: | 1881-7742 |
| Popis: | Antioxidant therapy has a potential to be introduced as therapeutic modality for chronic obstructive pulmonary disease (COPD) patients. This study aimed to determine the effect of antioxidant supplementation [ascorbic acid and N-Acetylcysteine (NAC)] on nutritional and antioxidant status in male COPD patients. A parallel and single blind randomised controlled clinical trial (RCT) was conducted at two medical centers in Kuala Lumpur, Malaysia. Seventy-nine subjects were recruited and randomly divided into four trial arms (i.e., NAC, vitamin C, NAC+vitamin C and control groups) for six mo. The primary outcome was changes in body mass index by estimating power of 90% and significance level of p |
| Databáze: | OpenAIRE |
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