Should Prostate Cancer Status Be Determined in Patients Undergoing Radical Cystoprostatectomy?
| Autor: | Tarık Esen, Faruk Özcan, Tayfun Oktar, Ömer Acar, Murad Celtik, Isın Kılıcaraslan, Murat Tunc, Oner Sanli |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Male
PCA3 Surgical margin medicine.medical_specialty Urology medicine.medical_treatment Adenocarcinoma Cystectomy Cystoprostatectomy Diagnosis Differential Intraoperative Period Prostate cancer Prostate medicine Humans Neoplasm Invasiveness Aged Neoplasm Staging Retrospective Studies Prostatectomy Carcinoma Transitional Cell Bladder cancer medicine.diagnostic_test business.industry Incidence Prostatic Neoplasms Rectal examination Middle Aged medicine.disease medicine.anatomical_structure Urinary Bladder Neoplasms business Follow-Up Studies |
| Zdroj: | Urologia Internationalis. 77:307-310 |
| ISSN: | 1423-0399 0042-1138 |
| Popis: | Introduction: We estimate the frequency of prostate cancers detected incidentally in radical cystoprostatectomy specimens and discuss whether the prostate cancer status should be determined in patients undergoing radical cystoprostatectomy. Materials and Methods: A total of 97 radical cystoprostatectomies without evidence of prostate cancer on digital rectal examination were performed for transitional cell carcinomas of the bladder between January 2001 and May 2004. The mean patient age at the time of surgery was 66.9 ± 9.52 (range 49–75) years. Results: The overall incidence of prostate cancer detected in radical cystoprostatectomy specimens was 21.6% (21/97 specimens). The mean tumor volume was found to be 0.93 ± 0.81 ml. The tumor volume was >0.5 ml in 12 cases (57.1%). The surgical margin was negative in all cases, and the disease was organ confined in 20 patients (95.2%). Capsular invasion was evident in 2 patients (9.5%), 1 of whom had lymph-node-positive disease. Conclusions: Despite the high prevalence of incidental prostate carcinomas among patients with bladder cancer undergoing cystoprostatectomy, the vast majority of the cancers are organ confined. However, the prostate cancer status should be determined on the basis of digital rectal examination and prostate-specific antigen in patients undergoing radical cystoprostatectomy – especially if prostate-sparing cystectomy is planned. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|