Comprehensive Analysis of the Real Lifestyles of T1D Patients for the Purpose of Designing a Personalized Counselor for Prandial Insulin Dosing

Autor: Pavlina Pithova, Katerina Stechova, Petr Cikl, Lenka Lhotska, J. Hlubik
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Blood Glucose
Male
obesity
Time Factors
endocrine system diseases
type 1 diabetes
medicine.medical_treatment
Saturated fat
Pilot Projects
Overweight
0302 clinical medicine
Body Fat Measurement
Medicine
Insulin
Drug Dosage Calculations
030212 general & internal medicine
prandial insulin bolus
Nutrition and Dietetics
digestive
oral
and skin physiology
Middle Aged
Postprandial Period
Mobile Applications
Postprandial
Treatment Outcome
Female
medicine.symptom
lcsh:Nutrition. Foods and food supply
Adult
medicine.medical_specialty
postprandial glycaemia
030209 endocrinology & metabolism
lcsh:TX341-641
Proof of Concept Study
Article
03 medical and health sciences
Carbohydrate counting
Young Adult
Insulin Infusion Systems
Internal medicine
Dietary Carbohydrates
overweight
Humans
Hypoglycemic Agents
Exercise
Life Style
Type 1 diabetes
business.industry
carbohydrate counting
Blood Glucose Self-Monitoring
Feeding Behavior
mobile application
medicine.disease
Obesity
Diabetes Mellitus
Type 1
business
diet
Energy Metabolism
Biomarkers
Cell Phone
Food Science
Zdroj: Nutrients
Volume 11
Issue 5
Nutrients, Vol 11, Iss 5, p 1148 (2019)
ISSN: 2072-6643
Popis: Post-prandial hyperglycemia is still a challenging issue in intensified insulin therapy. Data of 35 T1D patients during a four-week period were analyzed: RT-CGM (real time continuous glucose monitoring) record, insulin doses, diet (including meal photos), energy expenditure, and other relevant conditions. Patients made significant errors in carbohydrate counting (in 56% of cooked and 44% of noncooked meals), which resulted in inadequate insulin doses. Subsequently, a mobile application was programmed to provide individualized advice on prandial insulin dose. When using the application, a patient chooses only the type of categorized situation (e.g., meals with other relevant data) without carbohydrates counting. The application significantly improved postprandial glycemia as normoglycemia was reached in 95/105 testing sessions. Other important findings of the study include: A high intake of saturated fat (median: 162% of recommended intake)
a low intake of fiber and vitamin C (median: 42% and 37%, respectively, of recommended intake)
an increase in overweight/obesity status (according to body fat measurement), especially in women (median of body fat: 30%)
and low physical activity (in 16/35 patients). The proposed individualized approach without carbohydrate counting may help reach postprandial normoglycemia but it is necessary to pay attention to the lifestyle habits of T1D patients too.
Databáze: OpenAIRE
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