Antenatal glucocorticoid treatment is not associated with long-term metabolic risks in individuals born before 32 weeks of gestation
Autor: | M J J, Finken, M G, Keijzer-Veen, F W, Dekker, M, Frölich, F J, Walther, J A, Romijn, B J, van der Heijden, J M, Wit, G J, van Steenbrugge |
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Přispěvatelé: | Pediatric surgery, ICaR - Ischemia and repair, Other departments, Other Research, Neonatology, General Paediatrics, Plastic, Reconstructive and Hand Surgery, Pediatrics |
Jazyk: | angličtina |
Rok vydání: | 2008 |
Předmět: |
Male
Pediatrics medicine.medical_specialty Offspring Renal function Blood Pressure Gestational Age Prenatal care Betamethasone Young Adult Pregnancy Internal medicine Medicine Humans Adverse effect Glucocorticoids business.industry Infant Newborn Obstetrics and Gynecology Gestational age Prenatal Care General Medicine medicine.disease Lipids Endocrinology Prenatal Exposure Delayed Effects Pediatrics Perinatology and Child Health Body Composition Gestation Female Insulin Resistance business Infant Premature medicine.drug Follow-Up Studies Glomerular Filtration Rate |
Zdroj: | Archives of Disease in Childhood-Fetal and Neonatal Edition, 93(6), F442-F447. BMJ Publishing Group Finken, M J J, Keijzer-Veen, M G, Dekker, F W, Frolich, M, Walther, F J, Romijn, J A, van der Heijden, B J & Wit, J M 2008, ' Antenatal glucocorticoid treatment is not associated with long-term metabolic risks in individuals born before 32 weeks of gestation ', Archives of Disease in Childhood-Fetal and Neonatal Edition, vol. 93, no. 6, pp. F442-F447 . https://doi.org/10.1136/adc.2007.128470 Archives of disease in childhood. Fetal and neonatal edition, 93(6), F442-F447. BMJ Publishing Group Archives of Disease in Childhood. Fetal and Neonatal Edition, 93, 442-447. BMJ Publishing Group |
ISSN: | 1359-2998 |
Popis: | BACKGROUND: A single course of maternal glucocorticoid treatment is effective in reducing neonatal mortality after preterm birth. However, in animals, maternal glucocorticoid treatment is associated with lifelong hyperglycaemia and hypertension, and impaired nephrogenesis in offspring. Findings from studies in humans on this topic are highly contradictory due to a number of methodological flaws, and renal function after glucocorticoid exposure has never been assessed. OBJECTIVES: To assess in individuals born |
Databáze: | OpenAIRE |
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