POLYMETABOLIC DISORDERS AFTER HYSTERECTOMY: A CHANCE OR A RULE?
| Autor: | N M Podzolkova, V. I. Podzolkov, T I Nikitina, A. E. Bragina |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Hysterectomy business.industry Insulin medicine.medical_treatment Diastole Physiology Blood lipids RM1-950 medicine.disease metabolic syndrome Basal (phylogenetics) Endocrinology Blood pressure post-hysterectomy syndrome RC666-701 Internal medicine Diseases of the circulatory (Cardiovascular) system Medicine Pharmacology (medical) Therapeutics. Pharmacology Metabolic syndrome Cardiology and Cardiovascular Medicine business Body mass index |
| Zdroj: | Racionalʹnaâ Farmakoterapiâ v Kardiologii, Vol 7, Iss 3, Pp 294-299 (2016) |
| ISSN: | 2225-3653 1819-6446 |
| Popis: | Aim. To study the dynamic of metabolic disorders in patients after hysterectomy with intact ovaries. Material and methods. 104 women (aged 44.0±2.1) after hysterectomy with intact ovaries were examined. All patients were split into three subgroups according to time after hysterecto- my (1, 3, and 5 years). 25 women (aged 43.0±1.6) with normal menstrual function were included into the control group. Blood pressure (BP) levels and body mass index were measured. Serum lipids profile, plasma levels of immune-reactive insulin (IRI) and C-peptide were investigated in fasting condition and after oral glucose tolerance test. Results. Increase in time after hysterectomy was associated with significant elevation of body mass index, systolic and diastolic BP , basal and stimulated IRI and C-peptide levels, as well as serum levels of total cholesterol and low density lipoprotein cholesterol. These parameters had significant positive correlations with time after hysterectomy. Conclusion. Polymetabolic disorders were more prominent in patients with longer time after hysterectomy. These findings can be basis for definition of post-hysterectomy metabolic syndrome stages. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|