L-657,398, a novel antifungal agent: fermentation, isolation, structural elucidation and biological properties
Autor: | Sue Honeycutt, Robert E. Schwartz, George M. Garrity, Jerrold M. Liesch, Otto D. Hensens, Janet C. Onishi, Lauretta Zitano, Richard L. Monaghan, Robert A. Fromtling |
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Rok vydání: | 1988 |
Předmět: |
Antifungal
Antifungal Agents Pyrrolidines Chemical Phenomena medicine.drug_class chemistry.chemical_compound Biological property Drug Discovery medicine Mycelium Anisomycin Pharmacology biology food and beverages Biological activity biology.organism_classification Isolation (microbiology) Combinatorial chemistry carbohydrates (lipids) stomatognathic diseases Chemistry Aspergillus Biochemistry chemistry Fermentation Aspergillus ochraceus |
Zdroj: | The Journal of antibiotics. 41(12) |
ISSN: | 0021-8820 |
Popis: | L-657, 398 is a broad spectrum antifungal agent isolated from solid fermentation or from the mycelium of the liquid fermentation of Aspergillus ochraceus. Structurally, the compound is a novel pyrollidine related to anisomycin. |
Databáze: | OpenAIRE |
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