Prevalence of cryptosporidiosis in patients undergoing endoscopy: Evidence for an asymptomatic carrier state

Autor: William G. Roberts, Peter H.R. Green, Ann M. Ginsberg, Martin F. Carr, John Ma
Rok vydání: 1989
Předmět:
Zdroj: The American Journal of Medicine. 87:537-539
ISSN: 0002-9343
DOI: 10.1016/s0002-9343(89)80610-2
Popis: Purpose We sought to determine the presence of the parasite cryptosporidium in the duodenal aspirates of patients undergoing routine upper gastrointestinal endoscopy. Patients and methods The study consisted of 169 patients undergoing upper endoscopy or endoscopic retrograde cholangiopancreatography. Immunocompromised patients were not included in the study population. Samples were aspirated from the second portion of the duodenum. Biopsy specimens were also obtained. Three randomly passed stool samples were obtained from 75% of the patients who were found to have cryptosporidium in the duodenum. Results Overall, cryptosporidium oocysts were identified in 12.7% of patients. There was no significant difference in the prevalence of the parasite in any subgroup of procedure or symptom complex. Half of those (46.7%) with positive aspirates had demonstrable cryptosporidium in stool samples, although none of the patients had diarrhea. No patient had detectable cryptosporidium in biopsy samples of the duodenum. Conclusion The findings suggest a surprisingly high asymptomatic carrier rate for cryptosporidium.
Databáze: OpenAIRE