Outcome of the Respiratory Syncytial Virus related acute lower respiratory tract infection among hospitalized newborns: a prospective multicenter study
| Autor: | Kiray Bas, E., Koc, E., Hirfanoglu, I.M., Celik, U., Yalaz, M., Ergor, S.N., Duman, N., Iscan, B., Unal, S., Cakir, B., Ertugrul, S., Satar, M., Ozlu, F., Cevit, O., Bolat, F., Bilgili, G., Yigit, Y., Kurt, A., Tekgunduz, K.S., Caner, I., Yildiz, D., Kahvecioglu, D., Oygur, N., Erdogan, Y., Turkmen, M.K., Anik, A., Arsan, Saadet, Atasay, Begum, Ates, Can, Gokmen, Zeynel, Tunc, Turan, Akcakus, Mustafa, Zenciroglu, Aysegul, Akduman, Hasan, Cakir, Ufuk, ERDEVE, ÖMER, Alan, Serdar, Melekoglu, N.A., Celik, I., Korkmaz, A., Ozdemir, R., Karadag, A., Ozer, E., Ilhan, O., Mutlu, M., Aslan, Y., Erener- Ercan, T., Cetinkaya, M., Sahin, O., Akin, M.A., Okumus, N., Demirel, G., Kilic, A., Turkoglu-Unal, E., Bulbul, A., Takci, S., Anuk-Ince, D., Ciftdemir, N.A., Acunas, B., Ozkan, H., Koksal, N., Okulu, E., Demir, N., Tuncer, O., Dizdar, E.A., Oguz, S., Dilmen, U., Bozkaya, D., Sivasli, E. |
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| Přispěvatelé: | Alan, S., Neonatal Intensive Care Unit, Hitit University Corum Training and Research Hospital, Vedat Dolakay Cad. No: 90A/16 Gaziosmanpasa, Ankara, 06100, Turkey -- Erdeve, O., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Cakir, U., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Akduman, H., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Zenciroglu, A., Neonatal Intensive Care Unit, Dr Sami Ulus Maternity and Children Training and Research Hospital, Ankara, Turkey -- Akcakus, M., Division of Neonatology, Department of Pediatrics, Akdeniz University Medical School, Antalya, Turkey -- Tunc, T., Division of Neonatology, Department of Pediatrics, Gulhane Military School of Medicine, Ankara, Turkey -- Gokmen, Z., Neonatal Intensive Care Unit, Konya Training and Research Hospital, Konya, Turkey -- Ates, C., Department of Biostatistics, Ankara University School of Medicine, Ankara, Turkey -- Atasay, B., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Arsan, S., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Anik, A., Adnan Menderes University, Faculty of Medicine, Aydin, Turkey -- Turkmen, M.K., Adnan Menderes University, Faculty of Medicine, Aydin, Turkey -- Erdogan, Y., Akdeniz University, Medical School, Antalya, Turkey -- Oygur, N., Akdeniz University, Medical School, Antalya, Turkey -- Kahvecioglu, D., Ankara University, School of Medicine, Ankara, Turkey -- Yildiz, D., Ankara University, School of Medicine, Ankara, Turkey -- Caner, I., Ataturk University, Faculty of Medicine, Erzurum, Turkey -- Tekgunduz, K.S., Ataturk University, Faculty of Medicine, Erzurum, Turkey -- Kurt, A., Balikesir Ataturk Government Hospital, Balikesir, Turkey -- Yigit, Y., Celal Bayar University, Faculty of Medicine, Manisa, Turkey -- Bilgili, G., Celal Bayar University, Faculty of Medicine, Manisa, Turkey -- Bolat, F., Cumhuriyet University, Faculty of Medicine, Sivas, Turkey -- Cevit, O., Cumhuriyet University, Faculty of Medicine, Sivas, Turkey -- Ozlu, F., Cukurova University, Faculty of Medicine, Adana, Turkey -- Satar, M., Cukurova University, Faculty of Medicine, Adana, Turkey -- Ertugrul, S., Dicle University, Faculty of Medicine, Diyarbakir, Turkey -- Cakir, B., Ankara Children's Health Hematology Oncology Research Hospital, Ankara, Turkey -- Unal, S., Ankara Children's Health Hematology Oncology Research Hospital, Ankara, Turkey -- Iscan, B., Dokuz Eylul University, School of Medicine, Izmir, Turkey -- Duman, N., Dokuz Eylul University, School of Medicine, Izmir, Turkey -- Ergor, S.N., Ege University, Faculty of Medicine, Izmir, Turkey -- Yalaz, M., Ege University, Faculty of Medicine, Izmir, Turkey -- Celik, I., Etlik Zübeyde Hanim Women's Health Teaching and Research Hospital, Ankara, Turkey -- Celik, U., Etlik Zübeyde Hanim Women's Health Teaching and Research Hospital, Ankara, Turkey -- Hirfanoglu, I.M., Gazi University, Faculty of Medicine, Ankara, Turkey -- Koc, E., Gazi University, Faculty of Medicine, Ankara, Turkey -- Sivasli, E., Gaziantep University, Faculty of Medicine, Gaziantep, Turkey -- Melekoglu, N.A., Gaziantep University, Faculty of Medicine, Gaziantep, Turkey -- Kiray Bas, E., Gaziantep Children's Hospital, Gaziantep, Turkey -- Bozkaya, D., Hacettepe University, Faculty of Medicine, Ankara, Turkey -- Korkmaz, A., Hacettepe University, Faculty of Medicine, Ankara, Turkey -- Ozdemir, R., Inönü University, Faculty of Medicine, Malatya, Turkey -- Karadag, A., Inönü University, Faculty of Medicine, Malatya, Turkey -- Ozer, E., Tepecik Training and Research Hospital, Izmir, Turkey -- Ilhan, O., Tepecik Training and Research Hospital, Izmir, Turkey -- Mutlu, M., Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey -- Aslan, Y., Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey -- Erener- Ercan, T., Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey -- Cetinkaya, M., Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey -- Sahin, O., Kayseri Training and Research Hospital, Kayseri, Turkey -- Akin, M.A., Kayseri Training and Research Hospital, Kayseri, Turkey -- Okumus, N., Dr. Sami Ulus Maternity and Children Training and Research Hospital, Ankara, Turkey -- Demirel, G., Samsun Maternal and Child Health Hospital, Samsun, Turkey -- Kilic, A., Samsun Maternal and Child Health Hospital, Samsun, Turkey -- Turkoglu-Unal, E., Sisli Hamidiye Etfal Children Hospital, Istanbul, Turkey -- Bulbul, A., Sisli Hamidiye Etfal Children Hospital, Istanbul, Turkey -- Takci, S., Gaziosmanpasa University, Faculty of Medicine, Tokat, Turkey -- Anuk-Ince, D., Gaziosmanpasa University, Faculty of Medicine, Tokat, Turkey -- Ciftdemir, N.A., Trakya University, School of Medicine, Edirne, Turkey -- Acunas, B., Trakya University, School of Medicine, Edirne, Turkey -- Ozkan, H., Uludag University, Faculty of Medicine, Bursa, Turkey -- Koksal, N., Uludag University, Faculty of Medicine, Bursa, Turkey -- Okulu, E., Van Training and Research Hospital, Van, Turkey -- Demir, N., Yuzuncu Yil University, School of Medicine, Van, Turkey -- Tuncer, O., Yuzuncu Yil University, School of Medicine, Van, Turkey -- Dizdar, E.A., Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey -- Oguz, S., Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey -- Dilmen, U., Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey, Hitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Alan, S, Erdeve, O, Cakir, U, Akduman, H, Zenciroglu, A, Akcakus, M, Tunc, T, Gokmen, Z, Ates, C, Atasay, B, Arsan, S, Sakarya Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri Bölümü, Caner, İbrahim, Çukurova Üniversitesi |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
Pediatrics Neonatal intensive care unit Turkey viruses health care facilities manpower and services respiratory syncytial virus Infant Newborn Diseases Disease Outbreaks 0302 clinical medicine newborn Medicine 030212 general & internal medicine Prospective Studies Neonatal Intensive Care Unit Respiratory system Prospective cohort study Respiratory Tract Infections Cross Infection Respiratory tract infections Incidence (epidemiology) Obstetrics and Gynecology Obstetrics & Gynecology Prognosis Respiratory Syncytial Viruses Hospitalization Treatment Outcome Female medicine.drug Palivizumab medicine.medical_specialty education Respiratory Syncytial Virus Infections Antiviral Agents 03 medical and health sciences 030225 pediatrics Intensive care Intensive Care Units Neonatal Humans outbreak business.industry Infant Newborn Outbreak Infant nosocomial Newborn Pediatrics Perinatology and Child Health Respiratory Syncytial Virus Nosocomial business |
| Popis: | Taylor and Francis Ltd Aim: To determine the incidence and outcomes of respiratory syncytial virus (RSV)-related acute lower respiratory tract infection (ALRI) including morbidity, nosocomial infection and mortality among newborn infants who were admitted to the neonatal intensive care units (NICUs).Methods: A multicenter, prospective study was conducted in newborns who were hospitalized with community acquired or nosocomial RSV infection in 44 NICUs throughout Turkey. Newborns with ALRI were screened for RSV infection by Respi-Strip®-test. Main outcome measures were the incidence of RSV-associated admissions in the NICUs and morbidity, mortality and epidemics results related to these admissions.Findings: The incidence of RSV infection was 1.24% (n: 250) and RSV infection constituted 19.6% of all ALRI hospitalizations, 226 newborns (90.4%) had community-acquired whereas 24 (9.6%) patients had nosocomial RSV infection in the NICUs. Of the 250 newborns, 171 (68.4%) were full-term infants, 183 (73.2%) had a BW >2500 g. RSV-related mortality rate was 1.2%. Four NICUs reported seven outbreaks on different months, which could be eliminated by palivizumab prophylaxis in one NICU.Conclusion: RSV-associated ALRI both in preterm and term infants accounts an important percent of hospitalizations in the season, and may threat other high-risk patients in the NICU. © 2015 Taylor & Francis. Alan, S.; Neonatal Intensive Care Unit, Hitit University Corum Training and Research Hospital, Vedat Dolakay Cad. No: 90A/16 Gaziosmanpasa, Turkey; email: alanserdar@gmail.com |
| Databáze: | OpenAIRE |
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