Sequence analysis of nonulosonic acid biosynthetic gene clusters in Vibrionaceae and Moritella viscosa
| Autor: | Bjørn Altermark, Inger Lin Uttakleiv Ræder, Marie-Josée Haglund Halsør |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Sequence analysis Vibrionaceae Carbohydrates lcsh:Medicine Tandem mass spectrometry Article Evolution Molecular 03 medical and health sciences chemistry.chemical_compound Biosynthesis Bacterial Proteins Catalytic Domain Metabolomics lcsh:Science Gene Phylogeny Genetics Multidisciplinary VDP::Mathematics and natural science: 400::Chemistry: 440 030102 biochemistry & molecular biology biology lcsh:R Moritella viscosa Aliivibrio salmonicida Sugar Acids DNA Sequence Analysis DNA biology.organism_classification Enzymes Biosynthetic Pathways 030104 developmental biology chemistry VDP::Matematikk og Naturvitenskap: 400::Kjemi: 440 Multigene Family lcsh:Q Molecular modelling Bacteria Moritella |
| Zdroj: | Scientific Reports Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020) |
| ISSN: | 2045-2322 |
| Popis: | Nonulosonic acid (NulO) biosynthesis in bacteria is directed by nab gene clusters that can lead to neuraminic, legionaminic or pseudaminic acids. Analysis of the gene content from a set mainly composed of Aliivibrio salmonicida and Moritella viscosa strains reveals the existence of several unique nab clusters, for which the NulO products were predicted. This prediction method can be used to guide tandem mass spectrometry studies in order to verify the products of previously undescribed nab clusters and identify new members of the NulOs family. |
| Databáze: | OpenAIRE |
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