Postoperative serum urea is associated with 30-day mortality in patients undergoing emergency abdominal surgery
| Autor: | A. Hay, D St J O'Reilly, Donald C. McMillan, John Kinsella, J. M. Harten, Colin S. McArdle |
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| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty Clinical Biochemistry law.invention chemistry.chemical_compound Sex Factors law Intensive care Abdomen Medicine Humans Urea Postoperative Period Aged Creatinine business.industry Age Factors General Medicine Perioperative Odds ratio Middle Aged Intensive care unit Confidence interval Surgery Perfusion medicine.anatomical_structure chemistry Anesthesia Emergency Medicine Regression Analysis Female Kidney Diseases business Abdominal surgery |
| Zdroj: | Annals of clinical biochemistry. 43(Pt 4) |
| ISSN: | 0004-5632 |
| Popis: | Background: Emergency abdominal surgery carries considerable postoperative morbidity and mortality. Hypovolaemia is considered to be a cause of renal hypoperfusion, which is associated with a decreased clearance of serum urea and creatinine. This study examines whether the perioperative serum urea and creatinine concentrations are predictors of mortality in patients undergoing emergency abdominal surgery. Methods: Consecutive patients ( n=300) who underwent emergency abdominal surgery were studied. Age- and sex-specific reference intervals were used for the data analysis. Patients with incomplete biochemical ( n=51) or mortality data ( n=31) or with pre-existing renal failure ( n=9) were excluded from the analysis. Results: 209 patients were analysed, of whom 162 (78%) remained alive and 47 (22%) died following surgery. The non-survivors were older ( P Conclusions: These results indicate that an increased serum urea concentration, but not serum creatinine concentration, in the postoperative period is associated with an increase in 30-day mortality in patients undergoing emergency abdominal surgery. |
| Databáze: | OpenAIRE |
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