Catalytic acetoxylation of lactic acid to 2-acetoxypropionic acid, en route to acrylic acid

Autor:	Horacio J. Salavagione, N. Raveendran Shiju, Gadi Rothenberg, Marta Granollers, D. Robert Brown, Rolf Beerthuis
Přispěvatelé:	HCSC+ (HIMS, FNWI)
Rok vydání:	2015
Předmět:	chemistry.chemical_compound Acetic acid chemistry Silylation Dehydration reaction General Chemical Engineering Reagent Organic chemistry General Chemistry Heterogeneous catalysis Catalysis Acrylic acid Lactic acid
Zdroj:	Digital.CSIC. Repositorio Institucional del CSIC instname RSC Advances, 5(6), 4103-4108. Royal Society of Chemistry
ISSN:	2046-2069
Popis:	We present an alternative synthetic route to acrylic acid, starting from the platform chemical lactic acid and using heterogeneous catalysis. To improve selectivity, we designed an indirect dehydration reaction that proceeds via acetoxylation of lactic acid to 2-acetoxypropionic acid. This intermediate can then be pyrolized to acrylic acid. Acetic acid is used both as a reagent and a solvent in the first step, and may be recovered in the subsequent pyrolysis step. We tested a range of solid acid catalysts for the acetoxylation step (Y zeolites, sulfated zirconia, ion-exchange resins, sulfonated graphene, and various sulfonated silica gels and mixed oxides). Recycling studies were carried out for the most active catalysts. To enable quantitative analysis using gas chromatography we also developed a reliable silylation derivatization method, which is also reported. These results open opportunities for improving the biorenewable production of acrylic acid.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4c6d76ea6ad1a43a08af76ce8b3952 https://doi.org/10.1039/c4ra12695e Zobrazit plný text záznamu