Patient-controlled analgesia following caesarean section under general anaesthesia: a comparison of fentanyl with morphine
| Autor: | M. J. Douglas, Paul Howell, David R. Gambling, T. J. G. Pavy, Graham H. McMorland |
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| Rok vydání: | 1995 |
| Předmět: |
Adult
medicine.medical_specialty Vomiting medicine.medical_treatment Analgesic Anesthesia General Fentanyl Bolus (medicine) Double-Blind Method Pregnancy medicine Anesthesia Obstetrical Humans Caesarean section General anaesthesia Prospective Studies Pain Measurement Pain Postoperative Morphine business.industry Patient-controlled analgesia Cesarean Section Pruritus Analgesia Patient-Controlled Nausea General Medicine Surgery Anesthesiology and Pain Medicine Opioid Patient Satisfaction Anesthesia Analgesia Obstetrical Female Sleep Stages business medicine.drug |
| Zdroj: | Canadian journal of anaesthesia = Journal canadien d'anesthesie. 42(1) |
| ISSN: | 0832-610X |
| Popis: | This prospective, randomised, double-blind study compared PCA fentanyl with PCA morphine for post-Caesarean section analgesia. Following a standardised general anaesthetic, 37 women were allocated to receive either fentanyl (n = 18) or morphine (n = 19). The PCA was commenced after the women had been made comfortable in the postanaesthetic recovery room with the appropriate opioid solution (mean dose required = fentanyl 375 micrograms or morphine 16 mg). Initial PCA settings were bolus 1 ml (fentanyl 25 micrograms or morphine 1 mg), lockout time ten minutes, and no background infusion. Both analgesic solutions provided effective analgesia for a mean of 37 hr with high levels of patient satisfaction, and there were no differences in VAS scores for pain and patient satisfaction, or for side effects (nausea, itch, and sleepiness) between fentanyl or morphine. However, more patients in the fentanyl group required supplementary boluses or alterations to the PCA settings (13/18 vs 4/19: P = 0.005), and one patient was removed from the study due to inadequate analgesia. We conclude that fentanyl is not recommended for routine PCA use following Caesarean section. |
| Databáze: | OpenAIRE |
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