Lower relapse rates with good post-transplant outcome in alcoholic liver disease: Experience from a living donor liver transplant center
| Autor: | Vipul Rastogi, Neeraj Saraf, Sanjay Goja, Sanjiv Saigal, S. Ramachandra, V. Raut, Narendra S. Choudhary, Rahul Rai, Amit Rastogi, Saurabh Mehrotra, Prashant Bhangui, Dheeraj Gautam, Arvinder S. Soin, Naveen Kumar, Sanjay Kumar Yadav |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Alcoholic liver disease Time Factors media_common.quotation_subject India Context (language use) Living donor Gastroenterology 03 medical and health sciences 0302 clinical medicine Recurrence Interquartile range Surveys and Questionnaires Internal medicine Living Donors medicine Humans 030212 general & internal medicine Liver Diseases Alcoholic media_common business.industry Middle Aged Hepatology Abstinence medicine.disease Post transplant Liver Transplantation Survival Rate Treatment Outcome Female 030211 gastroenterology & hepatology Health Facilities Living donor liver transplantation business |
| Zdroj: | Indian Journal of Gastroenterology. 35:123-128 |
| ISSN: | 0975-0711 0254-8860 |
| DOI: | 10.1007/s12664-016-0646-z |
| Popis: | Post-transplant relapse is a major factor influencing the long-term outcome in alcoholic liver disease (ALD) patients. The aim of this study was to evaluate the relapse rates following living donor liver transplantation (LDLT) in patients with ALD in the Indian context with strong family support. Of 458 patients who underwent LDLT for ALD, 408 were included in the study. Post-transplant relapse was determined by information provided by the patient and/or family by means of outpatient and e-mail questionnaire, supported by clinical/biochemical parameters/liver histopathology. All except one were males, with a mean age of 46.9 ± 8.5 years. The overall rate of relapse was 9.5 % at 34.7 months (interquartile range (IQR) 15–57.6), lower than that reported in the literature from the West. The relapse rate was higher in patients with a shorter duration of pre-transplant abstinence (17.4 % and 15.4 % for recipients with pre-transplant abstinence of |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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