Epilepsy surgery and neurocysticercosis: Assessing the role of the cysticercotic lesion in medically-refractory epilepsy
| Autor: | Jorge G. Burneo, Alejandro Escalaya |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Pediatrics Drug Resistant Epilepsy 030231 tropical medicine Neurocysticercosis Culprit Lesion 03 medical and health sciences Behavioral Neuroscience Epilepsy 0302 clinical medicine medicine Humans Epilepsy surgery Gliosis Hippocampal sclerosis business.industry medicine.disease Surgery Neurology Inclusion and exclusion criteria Anticonvulsants Female Neurology (clinical) medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Epilepsybehavior : EB. 76 |
| ISSN: | 1525-5069 |
| Popis: | There is increasing evidence of the existence of refractoriness to treatment with antiepileptic medications in those with NCC-related epilepsy. We performed a systematic review with the objective to determine the role of a cysticercotic lesion in this group of patients. We sought those manuscripts, including case reports, describing patients with NCC-related medically-intractable epilepsy who underwent epilepsy surgery and were seizure-free a year after. Only 10 manuscripts fulfilled inclusion and exclusion criteria. Three different clinical presentations were identified: 1) the cysticercotic lesion was epileptogenic, 2) there was dual pathology, including the cysticercotic lesion, with the other lesion usually being hippocampal sclerosis, and 3) the cysticercotic lesion was not related to the epileptogenic focus. In the case of an epileptogenic cysticercotic lesion, the presence of gliosis appeared to be the culprit for epileptogenicity. More studies using large cohorts of patients might be able to confirm our findings. This article is part of a Special issue entitled “Neurocysticercosis and Epilepsy”. |
| Databáze: | OpenAIRE |
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