Highly clarithromycin-resistant Helicobacter pylori infection in asymptomatic children from a rural community of Cajamarca-Peru

Autor: Victor Zavaleta-Gavidia, Fernando Palacios-Cuervo, Juana del Valle-Mendoza, Angela Cornejo-Tapia, Andrea Calderón-Rivera, Jorge Bazán-Mayra, Wilmer Silva-Caso, Fátima Espinal-Reyes, Saul Levy-Blitchtein, Luis J. del Valle, Carlos Palomares-Reyes, Miguel Angel Aguilar-Luis
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Male
Rural Population
Peptic ulcer disease
lcsh:Medicine
Gastroenterology
0302 clinical medicine
Clarithromycin
Peru
Prevalence
Child
lcsh:QH301-705.5
biology
Rural community
General Medicine
Clarithromycin resistant Helicobacter pylori
Anti-Bacterial Agents
RNA
Ribosomal
23S
Research Note
PCR
030220 oncology & carcinogenesis
Female
030211 gastroenterology & hepatology
medicine.symptom
medicine.drug
medicine.medical_specialty
Adolescent
Asymptomatic
General Biochemistry
Genetics and Molecular Biology
Water consumption
Helicobacter Infections
03 medical and health sciences
Internal medicine
Drug Resistance
Bacterial
medicine
Humans
In patient
lcsh:Science (General)
Helicobacter pylori
business.industry
Gastric disease
lcsh:R
biology.organism_classification
bacterial infections and mycoses
Cross-Sectional Studies
lcsh:Biology (General)
Mutation
business
lcsh:Q1-390
Zdroj: BMC Research Notes, Vol 11, Iss 1, Pp 1-6 (2018)
BMC Research Notes
ISSN: 1756-0500
Popis: Objective The objective of this study was to determine the prevalence of clarithromycin-resistant Helicobacter pylori in asymptomatic children in a rural community of Cajamarca (northern Peru). Results Helicobacter pylori was detected in 17.2% (49/285) of the samples. Unboiled water consumption the most frequent associated factor in patients with positive PCR for H. pylori infection (93.9%). Clarithromycin resistant mutations were found in 79.6% (39/49) of the positive samples for H. pylori. The most frequent mutation was A2142G (46.9%), followed by the double-mutation A2142G–A2143G (28.6%).
Databáze: OpenAIRE
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