Synthesis and Local Anesthetic Activity of Benzo[b]furan Derivatives

Autor:	Abbas Shafiee, A. Khoyi, F. Savabi, A. Rezvani, M. Farrokhsiar
Rok vydání:	1978
Předmět:	Mice chemistry.chemical_compound Local anesthetic medicine.drug_class Stereochemistry Chemistry Furan medicine Animals Pharmaceutical Science Rabbits Anesthetics Local Benzofurans
Zdroj:	Journal of Pharmaceutical Sciences. 67:125-127
ISSN:	0022-3549
DOI:	10.1002/jps.2600670136
Popis:	Several 2-dialkylaminoethyl 3-methyl-2-benzo[ b ]furancarboxylates, 2-dialkylaminoethyl 3-methyl-2-benzo[ b ]furanca1bamates, and 3-methyl-2-benzo[ b ]furancarboxamided erivatives were prepared and tested for local anesthetic activity. Piperidinoethyl 3-methyl-2-benzo[ b ]furancarbamate, 2-diethylaminoethyl 3-methyl-2-benzo[ b ]-furancarboxylate, and N-(2-diethylaminoethyl)-3-methyl-2-benzo[ b ]-furancarboxamide were the most potent.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7dfaeb336b42354f1ffd4bcac45c7e https://doi.org/10.1002/jps.2600670136 Zobrazit plný text záznamu Plný text