Transdermal auricular vagus stimulation for the treatment of postural tachycardia syndrome
| Autor: | Raffaello Furlan, Franca Barbic, Dana Shiffer, Maura Minonzio, Andrea Bisoglio, Alberto Porta, Luis E. Okamoto, Stefano Rigo, André Diedrich, Italo Biaggioni, Vasile Urechie, Emily C Smith, Beatrice Cairo |
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| Rok vydání: | 2021 |
| Předmět: |
Tachycardia
Fatigue Syndrome Chronic Lightheadedness Endocrine and Autonomic Systems business.industry Chronic pain Orthostatic intolerance medicine.disease Article Postural Orthostatic Tachycardia Syndrome Cellular and Molecular Neuroscience Epilepsy Heart Rate Anesthesia Heart rate Orthostatic Intolerance medicine Palpitations Humans Neurology (clinical) medicine.symptom business Transdermal |
| Zdroj: | Auton Neurosci |
| ISSN: | 1566-0702 |
| DOI: | 10.1016/j.autneu.2021.102886 |
| Popis: | Postural Tachycardia Syndrome (POTS) is a chronic disorder characterized by symptoms of orthostatic intolerance such as fatigue, lightheadedness, dizziness, palpitations, dyspnea, chest discomfort and remarkable tachycardia upon standing. Non-invasive transdermal vagal stimulators have been applied for the treatment of epilepsy, anxiety, depression, headache, and chronic pain syndromes. Anti-inflammatory and immunomodulating effects after transdermal vagal stimulation raised interest for applications in other diseases. Patients with sympathetic overactivity, reduced cardiac vagal drive and presence of systemic inflammation like POTS may benefit from tVNS. This article will address crucial methodological aspects of tVNS and provide preliminary results of its acute and chronic use in POTS, with regards to its potential effectiveness on autonomic symptoms reduction and heart rate modulation. |
| Databáze: | OpenAIRE |
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