Associations between concussion and risk of diagnosis of psychological and neurological disorders: a retrospective population-based cohort study
| Autor: | Robert B. Tate, Heather J. Prior, Jeff Leiter, Marc P. Morissette, John G. Wade |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Adolescent Population Neuropsychological Tests Risk Assessment Young Adult Risk Factors Concussion Epidemiology medicine Dementia Humans education Brain Concussion Original Research Proportional Hazards Models Retrospective Studies lcsh:R5-920 education.field_of_study business.industry Hazard ratio public health Public Health Environmental and Occupational Health Manitoba Middle Aged medicine.disease Mood Anxiety epidemiology Female medicine.symptom Nervous System Diseases lcsh:Medicine (General) Family Practice business Cohort study |
| Zdroj: | Family Medicine and Community Health Family Medicine and Community Health, Vol 8, Iss 3 (2020) |
| ISSN: | 2009-8774 2305-6983 |
| Popis: | ObjectiveTo investigate associations between concussion and the risk of follow-up diagnoses of attention-deficit hyperactivity disorder (ADHD), mood and anxiety disorders (MADs), dementia and Parkinson’s disease.DesignA retrospective population-based cohort study.SettingAdministrative health data for the Province of Manitoba between 1990–1991 and 2014–2015.ParticipantsA total of 47 483 individuals were diagnosed with a concussion using International Classification of Diseases (ICD) codes (ICD-9-CM: 850; ICD-10-CA: S06.0). All concussed subjects were matched with healthy controls at a 3:1 ratio based on age, sex and geographical location. Associations between concussion and conditions of interest diagnosed later in life were assessed using a stratified Cox proportional hazards regression model, with adjustments for socioeconomic status and pre-existing medical conditions.Results28 021 men (mean age ±SD, 25±18 years) and 19 462 women (30±21 years) were included in the concussion group, while 81 871 men (25±18 years) and 57 159 women (30±21 years) were included in the matched control group. Concussion was associated with adjusted hazard ratios of 1.39 (95% CI 1.32 to 1.46, pConclusionConcussion was associated with an increased risk of diagnosis for all four conditions of interest later in life. |
| Databáze: | OpenAIRE |
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