Exclusive enteral nutrition continues to be first line therapy for pediatric Crohn's disease in the era of biologics

Autor: M.I. Vicioso Recio, M.J. Serrano Nieto, C. Sierra Salinas, S. Lacasa Maseri, Javier Blasco-Alonso, F. Girón Fernández-Crehuet, Víctor Manuel Navas-López
Jazyk: Spanish; Castilian
Rok vydání: 2015
Předmět:
Zdroj: Anales de Pediatría (English Edition), Vol 83, Iss 1, Pp 47-54 (2015)
ISSN: 2341-2879
Popis: Background: Exclusive enteral nutrition (EEN) has been shown to be more effective than corticosteroids in achieving mucosal healing without having their side effects. Objectives: To determine the efficacy of EEN in terms of inducing clinical remission in newly diagnosed CD children and to study the efficacy of this therapeutic approach in improving the degree of intestinal mucosa inflammation. Materials and methods: The medical records of patients with newly diagnosed Crohn's disease treated with EEN were reviewed retrospectively. The degree of mucosal inflammation was assessed by fecal calprotectin (FC). Remission was defined as a PCDAI
Databáze: OpenAIRE