Syphilis Infection during pregnancy: fetal risks and clinical management
| Autor: | Angelo Licameli, Carmen De Luca, Terryann Spagnuolo, Giovanni Scambia, Ilenia Mappa, Marco De Santis, Gianluca Straface |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
Infectious Disease Transmission Prenatal diagnosis Dermatology Review Article lcsh:Gynecology and obstetrics lcsh:Infectious and parasitic diseases Congenital Pregnancy medicine Vertical Humans lcsh:RC109-216 Syphilis Pregnancy Complications Infectious lcsh:RG1-991 Perinatal Mortality Fetus Maternal Transmission business.industry Obstetrics Syphilis Congenital Low Birth Weight Infectious Infant Newborn Obstetrics and Gynecology Gestational age Infant Infant Low Birth Weight medicine.disease Newborn Infectious Disease Transmission Vertical Pregnancy Complications Low birth weight Infectious Diseases Congenital syphilis Settore MED/40 - GINECOLOGIA E OSTETRICIA Settore MED/40 Premature Birth Female medicine.symptom business |
| Zdroj: | Infectious Diseases in Obstetrics and Gynecology Infectious Diseases in Obstetrics and Gynecology, Vol 2012 (2012) |
| ISSN: | 1098-0997 |
| Popis: | Congenital syphilis is still a cause of perinatal morbidity and mortality. Untreated maternal infection leads to adverse pregnancy outcomes, including early fetal loss, stillbirth, prematurity, low birth weight, neonatal and infant death, and congenital disease among newborns. Clinical manifestations of congenital syphilis are influenced by gestational age, stage of maternal syphilis, maternal treatment, and immunological response of the fetus. It has been traditionally classified in early congenital syphilis and late congenital syphilis. Diagnosis of maternal infection is based on clinical findings, serological tests, and direct identification of treponemes in clinical specimens. Adequate treatment of maternal infection is effective for preventing maternal transmission to the fetus and for treating fetal infection. Prenatal diagnosis of congenital syphilis includes noninvasive and invasive diagnosis. Serological screening during pregnancy and during preconception period should be performed to reduce the incidence of congenital syphilis. |
| Databáze: | OpenAIRE |
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