Efficacy of Patient-Delivered Partner Medication in the Treatment of Sexual Partners in Uganda
| Autor: | Elisabeth Faxelid, Fred Nuwaha, Bengt Höjer, Fred Kambugu, Peter S. J. Nsubuga |
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| Rok vydání: | 2001 |
| Předmět: |
Adult
Male Microbiology (medical) Sexually transmitted disease medicine.medical_specialty Referral Sexually Transmitted Diseases Dermatology law.invention Randomized controlled trial law Internal medicine Odds Ratio medicine Humans Uganda Referral and Consultation Gynecology Chi-Square Distribution Intention-to-treat analysis business.industry Public Health Environmental and Occupational Health Odds ratio Patient Acceptance of Health Care Sexual Partners Treatment Outcome Infectious Diseases Relative risk Female Contact Tracing business Chi-squared distribution Contact tracing |
| Zdroj: | Sex Transm Dis. 28:105-110 |
| ISSN: | 0148-5717 |
| DOI: | 10.1097/00007435-200102000-00008 |
| Popis: | Patient-based partner referral (PBPR) which is the main method for treating sexual partners of patients with sexually transmitted diseases (STDs) has limited effectiveness. The authors compared the efficacy of PBPR with patient-delivered partner medication (PDPM) among patients attending the Mulago STD clinic in Kampala Uganda. A total of 383 patients (187 women 196 men) with STDs were randomized to the PBPR or PDPM group. The proportion of sexual partners treated in either group was compared using the chi-square statistic by intention to treat for partners whose follow-up status was unknown. The two groups had similar background characteristics. Of the 237 partners elicited 176 (74%) were reported treated in the PDPM group. In the PBPR group in which 234 partners were elicited 79 (34%) were referred to the treatment clinic. This difference was statistically significant (risk ratio [RR] 2.44; 95% confidence interval [CI] 1.95-3.07; P < 0.001). Furthermore PDPM was more effective than PBPR for women and for casual partners for whom PBPR is considered difficult. For women 86 of 103 partners in the PDPM group were reported treated compared with 23 of 104 partners in the PBPR group (RR 4.55; 95% CI 2.92-7.08; P < 0.001). For casual partners 18 of 51 (34%) were reported treated in the PDPM group compared with only three of 45 partners (7%) who were referred in the PBPR group (RR 1.43; 95% CI 1.40-2.65; P < 0.01). Patient-delivered partner medication is more effective than patient-based partner referral in the treatment of sexual partners. (authors) |
| Databáze: | OpenAIRE |
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