The Role of Varicocele in Male Factor Subfertility
| Autor: | Boback M. Berookhim, Dillon Sedaghatpour |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Infertility
Male medicine.medical_specialty Urology medicine.medical_treatment Population Varicocele 030232 urology & nephrology Semen analysis 03 medical and health sciences 0302 clinical medicine medicine Humans education Infertility Male Gynecology Azoospermia education.field_of_study Pregnancy 030219 obstetrics & reproductive medicine Assisted reproductive technology medicine.diagnostic_test Obstetrics business.industry Patient Selection Retrospective cohort study General Medicine medicine.disease business |
| Zdroj: | Current urology reports. 18(9) |
| ISSN: | 1534-6285 |
| Popis: | Varicocele may play a significant role in a subset of patients presenting with male factor infertility. Despite its relatively high prevalence amongst subfertile men, there has been controversy over the effectiveness of surgical treatments, patient selection, and when to administer treatment, particularly in the era of assisted reproductive technology. In line with earlier finding, recent evidence strongly suggests that varicocelectomy improves pregnancy rates and semen parameters. The currently available literature still does not clearly elucidate the answer to this question, due to flaws in retrospective study design. Patients undergoing subinguinal microsurgical varicocelectomy appear to have the highest pregnancy rates, and lowest complication rates, compared to other surgical approaches. Current research has given us a better understanding of the relationship between varicocele and infertility. Amongst men presenting with semen analysis abnormalities and varicoceles, including those patients presenting with non-obstructive azoospermia or couples with a significant male factor component failing previous attempts at in vitro fertilization, varicocelectomy may improve take home baby rates. More robust, prospective, controlled studies are needed to further clarify the population of subfertile men with varicocele most likely to benefit from varicocelectomy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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