In vitro large diameter bowel anastomosis using a temperature controlled laser tissue soldering system and albumin stent
Autor: | Joseph M. Klausner, Yaron Rabi, Abraham Katzir, Micha Rabau, David Spector, Amos A. Hardy, Irena Vasserman |
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Rok vydání: | 2009 |
Předmět: |
medicine.medical_specialty
Materials science Swine medicine.medical_treatment Dermatology Anastomosis law.invention Random Allocation chemistry.chemical_compound law Albumins Tensile Strength Intestine Small medicine Animals Tissue soldering Large diameter Probability Laser Coagulation Anastomosis Surgical Suture Techniques Temperature Albumin Stent Laser Surgery Disease Models Animal chemistry Soldering Stents Indocyanine green |
Zdroj: | Lasers in Surgery and Medicine. 41:504-508 |
ISSN: | 1096-9101 0196-8092 |
Popis: | Background and Objective In today's age of advancing surgical technology, there is a need for better and simpler methods of tissue bonding. The use of lasers for tissue welding or soldering is one of these sutureless methods. In 30 years of laser tissue bonding (LTB) research, published reports of cylindrical organ anastomosis were limited to small diameters. The tension resisted by the anastomosis, which is caused by the intraluminal pressure, is also proportional to the organ diameter. Therefore the anastomosis of large diameter organs requires significantly stronger mechanical strength. The aim of this study is to demonstrate such an anastomosis. Materials and Methods In vitro anastomosis of porcine small bowel was performed by either LTB or sutures. Anastomosis in the laser group (number of samples, n = 15) included two main stages of soldering. The bowel edges were approximated over a solid albumin stent and heated with a temperature controlled GaAs laser system to 75°C. This was followed by spreading liquid albumin on the anastomotic line and heating by the same system again to 75°C. The control group (n = 5) was sutured anastomosis. All anastomoses were assessed by burst pressure measurement. Results The burst pressure of the laser group attained 170±40 mmHg which was significantly higher than that of the sutured group 83±37 mmHg (P |
Databáze: | OpenAIRE |
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