Pneumomediastinum in dermatomyositis itself is not a poor prognostic factor: report of a case and review of the literature
Autor: | Daitaro Kurosaka, Kenichiro Hirai, Akio Yamada, Isamu Kingetsu, Ken Yoshida |
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Rok vydání: | 2008 |
Předmět: |
Adult
Male myalgia medicine.medical_specialty Immunology Dermatomyositis Rheumatology medicine Humans Immunology and Allergy Pneumomediastinum Myopathy Mediastinal Emphysema business.industry Interstitial lung disease respiratory system medicine.disease Dermatology Rash Subcutaneous Emphysema respiratory tract diseases Surgery Antirheumatic Agents Cyclosporine Prednisolone medicine.symptom business Subcutaneous emphysema medicine.drug |
Zdroj: | Rheumatology International. 28:913-917 |
ISSN: | 1437-160X 0172-8172 |
DOI: | 10.1007/s00296-008-0548-1 |
Popis: | We describe a 38-year-old man who presented with proximal muscle weakness, myalgia, polyarthralgia, and skin rash and was diagnosed as having dermatomyositis (DM). The patient's symptoms improved with prednisolone therapy. However, myopathy relapsed and pneumomediastinum with subcutaneous emphysema developed. Pneumomediastinum with subcutaneous emphysema rapidly disappeared by the administration of ciclosporin. We reviewed the present case and previously reported cases regarding the clinical characteristics. All of the reported death cases were accompanied by interstitial lung disease (ILD). Although it has been reported that pneumomediastinum in DM can be fatal, the direct cause of patient's death was due to respiratory failure resulting from progressive ILD. Pneumomediastinum without ILD shows a good prognosis. |
Databáze: | OpenAIRE |
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