Autotransplantation of Inferior Parathyroid glands during central neck dissection for papillary thyroid carcinoma: A retrospective cohort study
| Autor: | Judy Jin, Jingqiang Zhu, Rixiang Gong, Zhen-hong Du, Yanping Gong, Zhihui Li, Tao Wei, Rui Chen |
|---|---|
| Jazyk: | angličtina |
| Předmět: |
Adult
Male Parathyroidectomy medicine.medical_specialty Adolescent Hypoparathyroidism medicine.medical_treatment Transplantation Autologous Cohort Studies Parathyroid Glands Thyroid carcinoma Young Adult Recurrence medicine Carcinoma Humans Postoperative Period Thyroid Neoplasms Central neck dissection Aged Retrospective Studies business.industry Incidence Thyroidectomy Neck dissection General Medicine Middle Aged medicine.disease Carcinoma Papillary Autotransplantation Surgery Dissection Thyroid Cancer Papillary Papillary thyroid carcinoma Lymph Node Excision Neck Dissection Female Lymph Nodes Parathyroids autotransplantation business Organ Sparing Treatments Neck Follow-Up Studies |
| Zdroj: | International Journal of Surgery. (12):1286-1290 |
| ISSN: | 1743-9191 |
| DOI: | 10.1016/j.ijsu.2014.11.001 |
| Popis: | Introduction: The management of inferior parathyroid glands during central neck dissection (CND) for papillary thyroid carcinoma (PTC) remains controversial. Most surgeons preserve inferior parathyroid glands in situ. Autotransplantation is not routinely performed unless devascularization or inadvertent parathyroidectomy occurs. This retrospective study aimed to compare the incidence of postoperative hypoparathyroidism and central neck lymph node (CNLN) recurrence in patients with PTC who underwent inferior parathyroid glands autotransplantation vs preservation in situ. Methods: This is a retrospective study which was conducted in a tertiary referral hospital. A total of 477 patients with PTC (pN1) who underwent total thyroidectomy (TT) and bilateral CND with/without lateral neck dissection were included. Patients' demographical characteristics, tumor stage, incidence of hypoparathyroidism, CNLN recurrence and the number of resected CNLN were analyzed. Results: Three hundred and twenty-one patients underwent inferior parathyroid glands autotransplantation (autotransplantation group). Inferior parathyroid glands were preserved in situ among 156 patients (preservation group). Permanent hypoparathyroidism rate was 0.9% (3/321) versus 3.8% (6/156) respectively (p = 0.028). Mean numbers of resected CNLN were 15 ± 3 (6–23) (autotransplantation group) versus 11 ± 3 (7–21) (preservation group) (p |
| Databáze: | OpenAIRE |
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