L-Arginine supplementation does not enhance blood flow and muscle performance in healthy and physically active older women
Autor: | Marcell Alysson Batisti Lozovoy, Cosme Franklim Buzzachera, Marcelo Bigliassi, Andreo Fernando Aguiar, Guilherme Atsushi Muraoka, Douglas Kratki da Silva, Rafael Mendes Pereira, Mario Carlos Welin Balvedi, Vanda Cristina Sanches, Renata Selvatici Borges Januário, Leandro Ricardo Altimari |
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Rok vydání: | 2015 |
Předmět: |
Functional training
Nutritional Supplementation Rest Medicine (miscellaneous) Vasodilation Blood Pressure Femoral artery Isometric exercise Performance-Enhancing Substances 030204 cardiovascular system & hematology Placebo Arginine Nitric Oxide Body Mass Index 03 medical and health sciences Basal (phylogenetics) 0302 clinical medicine Double-Blind Method medicine.artery medicine Humans Muscle Skeletal Aged Aged 80 and over Nutrition and Dietetics business.industry Resistance Training 030229 sport sciences Blood flow Middle Aged Anesthesia Dietary Supplements Female business Blood Flow Velocity |
Zdroj: | European journal of nutrition. 55(6) |
ISSN: | 1436-6215 |
Popis: | The purpose of this study was to examine the effects of acute l-arginine (l-arg) supplementation on peripheral vasodilatation and muscle performance in older women. In a double-blind, randomized, placebo-controlled study, 20 elderly women were randomly assigned in a double-blind fashion to either an l-arg (ARG, N = 10) or placebo (PLA, N = 10) group. During the first visit, both groups underwent a Doppler ultrasound exam (to assess the femoral artery vasodilatation) at rest (baseline), and immediately before and after the isokinetic strength test (performed at 80 min after supplementation). On the second and third visits, the groups completed a battery of muscle performance tests (to assess the isometric and functional strength), initiated at the same time point (80 min after supplementation). The femoral artery blood flow (ARG: 443.9 ± 42.8 vs. PLA: 373.1 ± 40.8 ml/min; P > 0.05) and area (ARG: 0.45 ± 0.03 vs. PLA: 0.41 ± 0.02 cm2; P > 0.05) were similar between the groups at basal conditions, and they remained unchanged after supplementation. Following exercise, blood flow increased ~160 % above the basal level, and there was no significant (P > 0.05) difference between the ARG and PLA groups. Additionally, there were no significant (P > 0.05) differences between the ARG and PLA groups for any strength variable (isokinetic, isometric, and functional). These results show that acute l-arg supplementation provides no ergogenic effect on blood flow and muscle performance in older women. |
Databáze: | OpenAIRE |
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