Cardioprotective Activity of Ganoderma lucidum Extract during Total Ischemia and Reperfusion of Isolated Heart
| Autor: | T. V. Lasukova, A. G. Arbuzov, L. I. Inisheva, Leonid N. Maslov, V. N. Burkova |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
Reishi Antioxidant Plant Extracts Chemistry medicine.medical_treatment Ischemia Heart Myocardial Reperfusion Injury Free Radical Scavengers General Medicine Rat heart Isolated heart Pharmacology medicine.disease Antioxidants General Biochemistry Genetics and Molecular Biology Rats medicine Animals Myocyte Myocytes Cardiac Rats Wistar Total ischemia Ganoderma lucidum |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 158:739-741 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-015-2851-7 |
| Popis: | The cardioprotective effects of Ganoderma lucidum extract were examined in experiments with global ischemia (45 min) and reperfusion (30 min) of isolated and perfused rat heart. The course of preventive administration of the extract in a dose of 400 mg/kg for 15 days diminished necrotic death of cardiomyocytes and reduced reperfusion contracture. Ganoderma lucidum extract demonstrated antioxidant properties. The authors believe that the cardioprotective properties of Ganoderma lucidum extract are largely determined by its antioxidant properties. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink