A numerical investigation of changes in lens shape during accommodation
| Autor: | Begoña Calvo, I. Cabeza-Gil, J. Grasa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Materials science Adolescent Science Finite Element Analysis 0206 medical engineering 02 engineering and technology Models Biological Article Computational biophysics 03 medical and health sciences 0302 clinical medicine Optics Lens Crystalline medicine Humans Multidisciplinary business.industry Accommodation Ocular Stiffness Radius 020601 biomedical engineering Elasticity Finite element method Biomechanical Phenomena medicine.anatomical_structure Multiple factors Lens (anatomy) 030221 ophthalmology & optometry Medicine medicine.symptom business Applied optics Biomedical engineering Accommodation Nucleus |
| Zdroj: | Zaguán. Repositorio Digital de la Universidad de Zaragoza Consejo Superior de Investigaciones Científicas (CSIC) Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021) Scientific Reports |
| Popis: | The purpose of this study was to investigate how the mechanical properties and geometry of the lens influence the changes in lens shape during accommodation. To do so, ex vivo stretching tests of the isolated lens were simulated via finite element analysis. In these tests, the lens is stretched from the accommodated state to the non-accommodated state. Several key characteristics of the lens were studied: the stiffness gradient of the lens material, the distribution of the capsule thickness, the mechanical properties of the capsule and the material comprising the lens, nucleus and cortex, and the influence of two different age-related lens geometries (17 and 29 y/o subjects). To determine the effects on the changes in lens shape during accommodation, changes in the anterior and posterior radius, the lens and nucleus thicknesses and the equatorial lens diameter were analysed. The results suggest that multiple factors exert statistically significant influences on how the lens changes its shape, but two factors predominate over the rest: the stiffness ratio between the nucleus and cortex and the stiffness of the capsule, specifically the posterior surface. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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