Variability of the Biological Activity of Oxidized Titanium Implants
Autor: | A. V. Krylatov, V. P. Ignatov, T. S. Petrovskaya, V. P. Shakhov, V. I. Vereschagin |
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Rok vydání: | 2012 |
Předmět: |
Materials science
Cell Survival Surface Properties Dermatologic Surgical Procedures Oxide chemistry.chemical_element Bone Marrow Cells Cell Count Zinc General Biochemistry Genetics and Molecular Biology Mice chemistry.chemical_compound Subcutaneous Tissue Coated Materials Biocompatible Osseointegration Aluminium Materials Testing Aluminum Oxide Animals Surface layer Cells Cultured Skin Dental Implants Titanium Inert Biological activity General Medicine Phosphorus Compounds chemistry Chemical engineering Microscopy Electron Scanning Implant Zinc Oxide Porosity |
Zdroj: | Bulletin of Experimental Biology and Medicine. 152:475-479 |
ISSN: | 1573-8221 0007-4888 |
DOI: | 10.1007/s10517-012-1556-4 |
Popis: | Oxidized titanium is a biologically inert material, but bioinertness reduces biomechanical characteristics of titanium implants. Modification of the structure of oxide surface layer of BT 5-1 titanium by increasing its thickness (by 1.7 times) and pore diameter (by 1.4 times) and by adding phosphorus, aluminum, and zinc oxides to its composition leads to radical modification of its biological characteristics. These implants acquire osteoinductive properties in in vivo systems not found in pure or oxidized BT 1-00 titanium and fairly well maintain in vitro growth of mesenchymal cells. |
Databáze: | OpenAIRE |
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