Variability of the Biological Activity of Oxidized Titanium Implants

Autor: A. V. Krylatov, V. P. Ignatov, T. S. Petrovskaya, V. P. Shakhov, V. I. Vereschagin
Rok vydání: 2012
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 152:475-479
ISSN: 1573-8221
0007-4888
DOI: 10.1007/s10517-012-1556-4
Popis: Oxidized titanium is a biologically inert material, but bioinertness reduces biomechanical characteristics of titanium implants. Modification of the structure of oxide surface layer of BT 5-1 titanium by increasing its thickness (by 1.7 times) and pore diameter (by 1.4 times) and by adding phosphorus, aluminum, and zinc oxides to its composition leads to radical modification of its biological characteristics. These implants acquire osteoinductive properties in in vivo systems not found in pure or oxidized BT 1-00 titanium and fairly well maintain in vitro growth of mesenchymal cells.
Databáze: OpenAIRE