COSMIC (Cohort Studies of Memory in an International Consortium): An international consortium to identify risk and protective factors and biomarkers of cognitive ageing and dementia in diverse ethnic and sociocultural groups

Autor: Tiffany F. Hughes, Kenichi Meguro, Shifu Xiao, Javier Santabárbara, Alexa S. Beiser, Henry Brodaty, Simone Reppermund, Kenneth Rockwood, Xia Li, John D. Crawford, Karen Ritchie, Marie-Laure Ancelin, Rhoda Au, Sudha Seshadri, Mary Ganguli, Yaakov Stern, Nicole A. Kochan, Carol Brayne, Tae Hui Kim, Ada Wt Fung, Isabelle Carrière, Ronald C. Petersen, Raúl López-Antón, Ji Won Han, Fiona E. Matthews, Candy H. Y. Wong, Antonio Lobo, Tze Pin Ng, Mindy J. Katz, Kaarin J. Anstey, Jennifer J. Manly, Juan Li, Richard B. Lipton, Blossom C. M. Stephan, Rosebud O. Roberts, Ki Woong Kim, Nicole Schupf, Hiroko H. Dodge, Nicolas Cherbuin, Darren M. Lipnicki, Peter Butterworth, Michelle M. Mielke, Linda Cw Lam, Qi Gao, Perminder S. Sachdev
Přispěvatelé: Centre for Healthy Brain Ageing, University of New South Wales [Sydney] (UNSW), Dementia Collaborative Research Centre, Department of Medicine (Geriatric Medicine & Neurology), Dalhousie University [Halifax], Department of Geriatric Psychiatry, Shanghai Jiao Tong University School of Medicine-Shanghai Mental Health Center, Institute of Psychology, Chinese Academy of Sciences [Beijing] (CAS), Department of Public Health and Primary Care, University of Cambridge [UK] (CAM), MRC Biostatistics Unit, Institute of Public Health, Institute of Health and Society, Newcastle University [Newcastle], Department of Epidemiology and Population Health, Yeshiva University- Albert Einstein College of Medicine [New York], Saul B. Korey Department of Neurology, Neuropsychiatrie : recherche épidémiologique et clinique (PSNREC), Université Montpellier 1 (UM1)-Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Faculty of Medicine, Imperial College London-St Mary's Hospital, Neurology Department, Boston University School of Medicine (BUSM), Boston University [Boston] (BU)-Boston University [Boston] (BU), Department of Biostatistics, Boston University [Boston] (BU), Department of Psychiatry, The Chinese University of Hong Kong [Hong Kong]-Tai Po Hospital, Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Department of Brain and Cognitive Sciences, Seoul National University College of Natural Sciences, Mayo Clinic College of Medicine-Mayo Alzheimer Disease Research Center, University of Pittsburgh School of Medicine, Pennsylvania Commonwealth System of Higher Education (PCSHE)-Pennsylvania Commonwealth System of Higher Education (PCSHE), Department of Neurology, Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Oregon Health and Science University [Portland] (OHSU), University of Michigan [Ann Arbor], University of Michigan System-University of Michigan System, Centre for Research on Ageing, Health and Wellbeing, Australian National University (ANU)-College of Medicine, Biology and Environment, Gerontology Research Programme, National University of Singapore (NUS)-Yong Loo Lin School of Medicine, Department of Geriatric Behavioral Neurology, Tohoku University Graduate School of Medicine, The Taub Institute for Research in Alzheimer's Disease and the Aging Brain, Columbia University [New York], The Gertrude H. Sergievsky Center, The Division of Epidemiology, Columbia University [New York]-Columbia Mailman School of Public Health, The Department of Neurology, Department of Medicine and Psychiatry, University of Zaragoza - Universidad de Zaragoza [Zaragoza], Centro de Investigación Biomédica en Red Salud Mental [Madrid] (CIBER-SAM), Catedrático de Psiquiatría, Hospital Clínico de Zaragoza-Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Department of Psychology and Sociology, Department of Preventive Medicine and Public Health, COSMIC, BMC, Ed., Université Montpellier 1 (UM1)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Seoul National University Bundang Hospital (SNUBH)
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Male
Gerontology
Aging
Internationality
[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology
education
Population
Clinical Neurology
Ethnic group
Disease
International consortium
Study Protocol
03 medical and health sciences
Data harmonisation
0302 clinical medicine
Risk Factors
Ethnicity
medicine
Humans
Dementia
Longitudinal Studies
[SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]
030212 general & internal medicine
Aged
Aged
80 and over
education.field_of_study
Social Identification
business.industry
Cognitive ageing
Confounding
[SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology
Mild cognitive impairment
General Medicine
Middle Aged
medicine.disease
Ageing
Cohort studies
Female
[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]
Neurology (clinical)
Cognition Disorders
business
Neurocognitive
030217 neurology & neurosurgery
Cohort study
Zdroj: BMC Neurology
BMC Neurology, BioMed Central, 2013, 13 (1), pp.165. ⟨10.1186/1471-2377-13-165⟩
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
ISSN: 1471-2377
DOI: 10.1186/1471-2377-13-165⟩
Popis: International audience; BACKGROUND: A large number of longitudinal studies of population-based ageing cohorts are in progress internationally, but the insights from these studies into the risk and protective factors for cognitive ageing and conditions like mild cognitive impairment and dementia have been inconsistent. Some of the problems confounding this research can be reduced by harmonising and pooling data across studies. COSMIC (Cohort Studies of Memory in an International Consortium) aims to harmonise data from international cohort studies of cognitive ageing, in order to better understand the determinants of cognitive ageing and neurocognitive disorders.Methods/design: Longitudinal studies of cognitive ageing and dementia with at least 500 individuals aged 60 years or over are eligible and invited to be members of COSMIC. There are currently 17 member studies, from regions that include Asia, Australia, Europe, and North America. A Research Steering Committee has been established, two meetings of study leaders held, and a website developed. The initial attempts at harmonising key variables like neuropsychological test scores are in progress. DISCUSSION: The challenges of international consortia like COSMIC include efficient communication among members, extended use of resources, and data harmonisation. Successful harmonisation will facilitate projects investigating rates of cognitive decline, risk and protective factors for mild cognitive impairment, and biomarkers of mild cognitive impairment and dementia. Extended implications of COSMIC could include standardised ways of collecting and reporting data, and a rich cognitive ageing database being made available to other researchers. COSMIC could potentially transform our understanding of the epidemiology of cognitive ageing, and have a world-wide impact on promoting successful ageing.
Databáze: OpenAIRE
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