A Coupled Phase-Temperature Model for Dynamics of Transient Neuronal Signal in Mammals Cold Receptor
| Autor: | Firman Ahmad Kirana, Irzaman Husein, Husin Alatas |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Physics Membrane potential Article Subject Differential equation Biomedical Engineering Biophysics Effective temperature Nonlinear differential equations Neuronal signaling 03 medical and health sciences 030104 developmental biology Phase model Cold receptor Biological system Saturation (chemistry) Simulation Research Article |
| Zdroj: | Journal of Biophysics |
| ISSN: | 1687-8019 1687-8000 |
| Popis: | We propose a theoretical model consisting of coupled differential equation of membrane potential phase and temperature for describing the neuronal signal in mammals cold receptor. Based on the results from previous work by Roper et al., we modified a nonstochastic phase model for cold receptor neuronal signaling dynamics in mammals. We introduce a new set of temperature adjusted functional parameters which allow saturation characteristic at high and low steady temperatures. The modified model also accommodates the transient neuronal signaling process from high to low temperature by introducing a nonlinear differential equation for the “effective temperature” changes which is coupled to the phase differential equation. This simple model can be considered as a candidate for describing qualitatively the physical mechanism of the corresponding transient process. |
| Databáze: | OpenAIRE |
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